The Exploratory Between "Salivary Amylase Activity Ratio"and Clinical Manifestion

Object iveSyndrome of deficiency of Spleen Qi as a common clinical syndrome, it combines different diseases, different patients can exhibit different clinical features, namely its diagnostic performance has obvious polymorphism."The activity of salivary amylase ratio" as to better reflect the essence of insufficiency of the features of the two auxiliary diagnostic index of, over the years by experts and scholars, and the deficiency of modern research has also shown that,"the activity of salivary amylase ratio" reduce also only in part of spleen-qi deficiency patients received positive results. Therefore, through the detailed observation and Analysis on spleen-qi deficiency patients "salivary amylase activity ratio and the relationship between the" four ", to further explore the salivary amylase activity ratio" to reflect the law of spleen-qi deficiency syndrome. At the same time, right before the Spleen-qi Deficiency Patients "salivary amylase activity ratio determination of saliva left" improved method of obtaining further demonstration of contrast.Methods1, The criteria for inclusion into the study are as follow:subjects are from the Guangzhou hospital of Traditional Chinese Medicine(both in-patient and out-patient wards)who was diagnosed as chronic gastritis, and discriminated as deficient Qi of Spleen (30), and the healthy normal group (20) for comparing.2, The traditional (the determinat ion of basic state)"salivary amylase load test" as a standard control. The two groups were evaluated in the basal state(no activity after wake up in the early morning,quiet and fasting) and non-basal sttate (wake up in the morning with normal activity, quiet and fasting), and in these two situations, the activities of salivary amylase before and after the stimulation of acid. Then calculated the ratio of the activity after acid stimulation/before acid stimulation,and analyzed the results with statistical method. And of course, fill in the registration sheets in details.3, Detailed comparison of the positive and the negative indicators of spleen-qi deficiency symptoms show the similarities and differences between the two groups of patients, analysis of clinical manifestations of different characteristics, trying to reveal the Spleen-qi Deficiency Patients "salivar\amylase activity ratio" and the relationship between the clinical performance.4, Using SPSS17.0for Windows statistical software to analyze the data,"t" test was used to compare measurement data, count data were compared with chi-square test, correlation between the symptoms and indices using rank correlation analysis.Results1, Spleen deficiency group basic state and non basal condition after acid stimulation of salivary amylase activity than before acid stimulation decreased significantly, acid before and after stimulation of enzyme activity and tnere was significant difference (P<0.05), healthy controls in the basal state and non basal condition after acid stimulation of salivary amylase activity than the acid stimulation were rising trend, the acid before and after stimulation of enzyme activity is also obvious differences (P<0.05), with statistical significance.2, Spleen deficiency group and normal group in the basal state or between non basic state before acid stimulation of salivary amylase activity in statistically there is considerable difference (P<0.05); spleen deficiency group in basal conditions or a basal condition after acid stimulation of enzyme activity ratio were significantly different (P<0.05), while the the normal group in basal conditions or a basal condition after acid stimulation of enzyme activity were not significantly different (P>0.05), no statistical significance.3, Spleen-qi deficiency of state before and after acid stimulation of salivary amylase activity changes and state before and after acid stimulation of salivary amylase activity changes consistent with the rate of70%, and the ratio between enzyme activity had no significant difference (P>0.05).4, Spleen deficiency group part of the main symptoms and was found: exhausted (50%), limb burnout (50.7%), body weight drowsiness (76.7%), vulnerable to the cold (73.3%), fresh (66.7%), dull stomachache, Wen Xi press (60%), flatulence (73.3%), belch, Hiccup (56.7%), pantothenic acid (50%), pale tongue fat has tooth seal (96.7%), Bo Bai (70%), pulse fine (66.7%), loss of appetite (40%), loose stools diarrhea (43.3%), nausea and vomiting (26.7%), chest pain, shortness of breath (46.7%).Conclusion1, The study of spleen deficiency patients basal condition after acid stimulation of salivary amylase activity decreased obviously, enzyme activity ratio is low, the results with previous research data consistency. Non basic state, spleen deficiency patients after acid stimulation of salivary amylase activity also drops obviously, the change in enzyme activity of each index and basal condition determination results consistent with the rate of70%, can be confirmed that the Spleen-qi Deficiency in the basal condition also have digestive insufficiency, parasympathetic hyperfunction and stress ability low.2, Spleen deficiency group and the healthy controls in basal condition and non basal condition acid before and after stimulation of salivary amylase activity ratio between group comparison shows,"salivary amylase load test" in the basal condition reflects the deficiency of essential feature and the basic state of the reaction of spleen qi deficiency syndrome essence feature is the presence of inconsistent.3, Spleen deficiency group of basal condition of salivary amylase activity ratio and foundation under the condition of self control, there are significant differences, but healthy controls in the basal condition of salivary amylase activity ratio and foundation of self control basic consistent state. Because the amount of sample is less, the basic state of "salivary amylase load test" results not as basic state of "salivary amylase load test results to reach consensus". 4, Clinical observation of spleen deficiency patients symptoms and "salivary amylase activity ratio determination of" positive rate has the close relation, further explanation on spleen deficiency syndrome of traditional Chinese medicine the accuracy, the strict exclusion and clip permits,"salivary amylase activity ratio" positive rate increased significantly, and validation from TCM rigor.