Effect Of Sodium Tanshinone ⅡA On Hemorheology In Patients With Acute Cerebral Infarction

Objective:To observe the effects of Sodium Tanshinone ⅡA on hemorheology in patients with Acute Cerebral Infarction.Methods:One hundred and eighteen patients with Acute Cerebral Infarction were randomly divided into a treatment group and a control group.The control group(57subjects)were treated with conventional therapy,and the treatment group(61subjects)were treated with Sodium Tanshinone ⅡA(60mg ivdrip qd)combined with conventional therapy.The total period of treatment was14days.Neurological functional deficit score (NDS) was assessed and hemorheological indexes were determined before and after the treatment.Results:There was abnormal hemorrheological properties in all patients with Acute Cerebral Infarction before treatment.The changes of indexes of hemorheology were obvious in the treatment group before and after treatment(P<0.05), conventional therapy had no obvious effect on hemorheology (P>0.05).There was significant differences between two groups after treatment(P<0.05).Clinical effect assessment results:In treatment group,total effective rate was90.16%, in control group,total effective rate was80.7%,there was significant differences between two groups after treatment(P<0.05).Conclusion:Hemorheological index can be improved significantly in patients with Acute Cerebral Infarction after being treated with Sodium tanshione ⅡA,which may contribute to the recovery of nerve function.