The Correlation Analysis Of CP/CPPS With Lower Urinary Tract Symptoms And Erectile Dysfunction

Objective:To investigate the correlation of CP/CPPS with lower urinary tract symptoms (LUTS) and erectile dysfunction (ED).Methods:The study randomly selected the period from March2011to January2012in the Second XiangYa Hospital urology outpatient treatment of CP/CPPS patients with LUTS of382cases, after screening, eligible and were followed up cases108case. According to age, patients were divided into three groups:≤35yrs (n=21),35-45yrs (n=59),≥45yrs (n=28). Diagnostic criteria according to the International Prostatitis Symptom Score (NIH chronic prostatitis symptom index, the NIH-CPSI), all patient with urinary frequency, urinary discomfort, perineal pain, discomfort and varying degrees of sexual dysfunction and other symptoms for at least three months. All cases, detailed history taking, comprehensive physical examination (including digital rectal examination), urine and prostatic routine examination; the exclusion of other lower urinary tract diseases, such as urinary tract infection, tuberculosis, stones, benign prostatic hyperplasia, prostate cancer, urethral stricture, bladder cancer and neurogenic bladder. Application of the NIH Chronic Prostatitis Symptom Index (NIH-CPSI) and symptom score, International Prostate Symptom Score (IPSS), as well as international erectile function score (IIEF-5),108 cases of patients with complete data were statistically analyzed.Results;1. The morbidity rate of ED was63.89%for all108patients.2. There were42.86%,64.41%and78.57%for each group of age:≤35yrs,35-45yrs and≥45yrs respectively. The morbidity rate of ED was related to the age.3. There were42.31%,62.26%,82.76%for mild LUTS, moderate LUTS and severe LUTS respectively. The morbidity rate of ED was related to the degree of LUTS.4. There was negative correlation between age and IIEF-5(r=-0.174, P<0.001), negative correlation between age and IPSS (r=-0.168, P<0.001), negative correlation between IPSS and IIEF-5((r=-0.285, P<0.001), After correcting for age, there was also correlation between IPSS and IIEF-5(r=-0.352, P<0.001).Conclusion:1. NIH-CPSI score and IIEF-5rating is correlation, CP/CPPS with the symptoms may be the reason caused by ED.2. There was moderate negative correlation among age, IPSS and ED, so age and LUTS were the impact factors to ED.3. LUTS was the independent risk factor to ED, and the severity of LUTS symptoms.