Drying Process The Change In Main Active Ingredients Of Radix Scrophularia

Scrophulariae radix department Scrophulariaceae plant scrophulari-Aceae root dry, with cooling blood to nourish yin,detoxification,Sanjie effect. Modern pharmacological studies have shown that, Scrophulariae radix has to enhance immunity, anti-tumor, blood pressure lowering,anti-oxidant,hepatoprotective, anti-gout, protect the nervous system and impr-ove memory in many aspects of the role.The chemical constituents isolated from Scrophulariae radix50mai-nly contains iridoid glycosides,phenylpropanoid glycosides, volatile oil and organic acids,19kinds of iridoid glycosides from Scrophulariae radix its compound nucleus to Harpagide for harpagoside and harpagide and6-O-methyl-catalpol, catalpol nucleus,1-dehydroxy-3,4-dihydroaucubigeinn and aucubin.The Scrophulariae radix cyclenic ethers terpene glycoside and phenylpropanoid glycosides are considered the active ingredients of the Scrophulariaceae.Commercial harpagoside content of the active ingre-dient in the Scrophulariaceae herbs from0.01%to0.2%, the difference of of their content difference of about twenty times, we can see that its com-position is not stability.Iridoid glycosides and phenylpropanoid glycosides susceptible to the influence of light, heat,oxygen and enzymes,and vulnerable to oxidation and hydrolysis. In the Scrophulariaceae medicine production,Scrophulari-aceae origin processing method for repeated long-term air dry and baked until browning and drying, the drying methods have certain effects on the chemical composition of the Scrophulariaceae herbs,and medicinal rot,microbialpollution problems.Acquisition of Enshi Hubei GAP origin of fresh Radix Scrophulariae in its herbs harvesting season, were used to air dry, oven drying and microwave vacuum drying Radix Scrophulariae drying process. In accordance with the2010version of the Ch.P under the provisions of the determination of different drying process Radix Scrophulariae moisture, total ash, water-soluble extract, alcohol extract, and the Harpagide, Aucubin,Angoroside-C,Catalpol and cinamic acid active active ingredient content analysis involved in the microwave vatu-um drying mysterious drying, oven drying Radix Scrophulariae differences of the main active ingredient, to further explore the feasibility of microwave vacuum drying technology applied to the Radix Scrophula-riae herbs, optimize the Radix Scrophulariae processing methods.The active substance during the drying process in order to better Radix Scrophulariae,60℃oven drying the Radix Scrophulariae required42hours as a reference.Fresh Scrophulariaceae packet dry, is divided into50℃and60℃,70℃and oven drying at80℃for fresh Scrophulariaceae to dry complete, th-is time every three hours sampling time, using HPLC of the content analysis for each sampling.The main active ingredient,harpagoside,Harpagide, Aucubin, Angor-oside-C, Catalpol the content of microwave vacuum drying of the Scrop-hulariaceae were higher than drying dry Scrophulariaceae and oven drying Scrophulariaceae, while cinnamic acid content of oven drying Scrophulariaceae higher air dry Scrophulariaceae Secondly, the microwa-ve vacuum drying Scrophulariaceae content at least. Research on the Scrophulariaceae different drying process results showed that the microwave vacuum drying herb of good quality air dry and oven dry, more suitable for the drying of fresh Scrophulariaceae.Four different temperatures, the Scrophulariaceae in the trends of each component is ba-sically the same. As the drying time, iridoid glycosides and phenylpropa-noid glycosides during the drying process is vulnerable to oxidation and hydrolysis decreased generate cinnamic acid or other ingredients.