Objective:By Interpretation method of soothing liver and strengthening spleen in treatment of chronic viral hepatitis (liver depression and spleen deficiency with damp heat type) in patients with clinical experiment, to study its effect on serum IL-4, and further explore the Interpretation method of soothing liver and strengthening spleen in treatment of chronic viral hepatitis (liver depression and spleen deficiency with damp heat syndrome) mechanism of action.Methods:all cases were observed of all comes from2011January to2012April,the First Affiliated Hospital of Heilongjiang University Of Chinese Medicine liver spleen and stomach outpatient chronic patients with hepatitis virus.In strict accordance with the inclusion criteria included60cases, which were randomly divided into control group and treatment group,30cases in each group of patients, a normal control group of30cases.The treatment group takes on Interpretation method of soothing liver and strengthening spleen prescription consisting of soothing liver and strengthening spleen interpretate method in the treatment of.The control group was given similar effect of Qingre capsules in treatment of hepatitis.Treatment for3months.To observe two groups of patients before and after treatment in patients with IL-4, the change of clinical comprehensive therapeutic effect, the main syndromes of traditional Chinese medicine to improve the situation, liver function and the changes of CHB-DNA. Create database, all data will be input into the database, the application of SPSS17.0statistical software package for data statistical analysis, counting material with X2inspection, measurement data using the t test, rank data using Ridit analysis.Results:1in chronic hepatitis B patients with serum IL-4levels were significantly higher than normal IL-4level (P<0.01).2treatment group and the control group were able to patients might have a very good improvement, comparison between groups (P>0.05), no significant difference, without statistical significance.3The experiment found, the treatment group and the control group can reduce the HBV-DNA quantitatively, the treatment group was significantly lower than the control group (P<0.05), with statistical significance.4in the treatment group and control group after treatment, the symptoms were obviously improved (P<0.01), with statistical significance.But the two groups had no difference (P>0.05), no statistical significance.5in the treatment group and the control group can make the level of IL-4increased, but the treatment group was more obvious (P<0.05).Conclusion:1Interpretation method of soothing liver and strengthening spleen can make the patient’s symptoms improved, with statistical significance.2Interpretation method of soothing liver and strengthening spleen with the comprehensive efficacy, but better than the control group, the comparison of the two have the difference of Statistics.3Interpretation method of soothing liver and strengthening spleen on patients with liver function has a very good improvement.4Interpretation method of soothing liver and strengthening spleen can make the level of IL-4decreased, and compared with the control group was more obvious, with statistical significance.5Interpretation method of soothing liver and strengthening spleen can decrease the content of HBV-DNA, and a control group was more obvious, with statistical significance. |