Clinical Study Of Interventional Therapy Of Ischemic Cerebrovascular Disease

Objective To study the short—term effect and the long—term effect ofinterventional therapy of ischemic cerebrovascular disease; observe the rate ofcomplications.Methods Choose427patients who met the diagnostic criteria of ischemiccerebrovascular disease; use DSA to understand the cerebrovascular stenosis,including narrow part, narrow degree; assess patients,nervous system function. Thendivide patients who are fit for interventional therapy into two groups randomly:interventional therapy group and simple drug treatment group. There were51cases ininterventional therapy group and63cases in simple drug treatment group. Follow upall patients for12months．Medical records were collected included：(1)Recurrenceand morbidity and TIA during the period of follow—ups；(2)NIHSS scale；(3) thepeaking of systolic velocity (Vs).Results1. There were333artery stenosis patients, which were77.99%of patients who met thediagnostic criteria of ischemic cerebrovascular disease;231carotid arteries stenosispatients（54.10%）;102vertebrobasilar arteries stenosis patients（23.89%）.2. Twelve months after treatment, compare interventional therapy group with simpledrug treatment group, there were significant differences between2groups,Vs(p＜0.05).3. Follow up all patients for12months, there were3ischemic cerebrovascular diseasecases in interventional therapy group (5.88%) and9ischemic cerebrovascular disease cases in simple drug treatment group, There were significant differences between2groups(p＜0.05).4. In NIHSS scores there were statistically significant differences between cerebralinfarction patients about2groups (P<0.05), which meant interventional therapy groupbetter than simple drug treatment group in improvement of nerve function.Conclusions Responsibility artery stenosis is an important factor in the pathogenesis ofischemic cerebrovascular disease. Interventional therapy is safe and effective methodsof treatment of ischemic cerebrovascular disease. Interventional therapy is better thansimple drug treatment in the short-term effect. But we need a longer time to follow-up,in order to compare two groups of long-term efficacy.