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OAB Symptom Score Table For BPH Treatment Guidance-related Research

Posted on:2013-04-27Degree:MasterType:Thesis
Country:ChinaCandidate:K J TongFull Text:PDF
GTID:2234330374998699Subject:Surgery
Abstract/Summary:PDF Full Text Request
Lower urinary tract symptoms (lower urinary symptoms, LUTS) is urination disorders collectively, including benign prostatic hyperplasia (benign prostatic hyperplasia, BPH) is LUTS caused by the most common disease in older men, not limited to urological Surgeon General practitioners need to often in the face of one of the diseases. In for LUTS scoring and Quality of life (QOL) of correlation analysis in the found, LUTS for life quality of effect is plagued patients and led its doctor of main causes, but its for life quality of effect and serious degree does not into is proportional to the IPSS, the cause is due to QOL is to patients of subjective feel for carrier, and IPSS is to doctor for patients symptoms of summary and experience judge for carrier, IPSS do for connection medical suffering from communication of bridge role has must defects, preliminary diagnosis and treatment on BPH/LUTS of direction deviation and misunderstanding. According to the survey, current doctor for BPH treatment of knowledge, the most serious mistakes that is isolated from LUTS and BPH, ignore the patient’s subjective experience, single factor in the treatment of benign prostatic hyperplasia (the relief of obstruction treated) as the only treatments for BPH, most have no access to proper and effective treatment in patients with BPH/LUTS. Therefore, seeking also to patients for doctors and patients led to a unified cognitive bias in order to get proper treatment in patients with BPH/LUTS assessment tools is extremely important. The purpose of this article is based on BPH/LUTS characteristics of various factors affecting the quality of life for patients, BPH/LUTS/OAB factor for people with problems of a dominant factor, introduced in the diagnosis and treatment of BPH/LUTS patients with overactive bladder (OAB) evaluation tools, analysis and discussion of its guidance role for initial diagnosis and treatment of BPH/LUTS.Purpose:1. Understand the concept of BPH/LUTS, staging, understand the correlation between BPH/LUTS and OAB, understand the concepts of BPH/LUTS/OAB factors and factors affecting the quality of life of patients, about how OAB application assessment tools introduced in the theoretical basis of diagnosis and treatment of BPH/LUTS.2. Describes international commonly used of several OAB symptoms of evaluation tools:Primary OAB Symptom Questionaire (PPBC), Primary OAB Symptom Questionaire (POSQ), Overactive Bladder-questionaire (OAB-q), Overactive Bladder Symptom Score (OABSS), urination diary card, and ICI urine incontinence questionnaire summary (ICIQ-SF), understanding its items, characteristic, significance, effective and handling of clinical.3. Statistical analysis the dependability between pure item of IPSS and QOL. Statistical analysis the dependability between IPSS1and QOL, IPSS2and QOL, analysis which symptoms has strongly effect with quality of life.4. Research analysis OAB-q, POSQ, OABSS and IPSS, relationship between of them and alloeosis rate before and after treatment.5.Integrating the advantage and disadvantage of each table, select as the representative, should be used for clinical, research analysis of the most advantage tool for guidance and evaluation of curative effect on the treatment of patients with BPH.Method:The search inquire into489man-times and getting2445questionnaires correlating with OAB for statistics data on the way that the patients filling in tables at clinic service.1. On September2007to January2012PLA subsection272hospital, and PLA464hospital urinary surgical has confirmed BPH non-surgery treatment outpatient, in get them agreed and told out complete purpose, time points and method by outpatient doctor complete IPSS, and QOL, and PPBC, and OAB-q, and OABSS, and ICIQ-SF table-sets, orders medication treatment visit after4week and the6week,4week visits complex filled above all table again. When6weeks visits complete the QOL. Completed the first completed231,167people completed visits to fill in for the second time, three visits and fill in the information are complete the98people, full of statistical analysis of the available information of91.2. the Patients that got all treatment research datas were divided into two groups by the time point, the first receivd pure BPH treatment using5a reductase inhibitor and a receptor blocker, the other group, at the last two weeks by the prospective study under OABSS assessment results (urgent micturition score>2, OABSS score>3) against OAB treatment by M receptor blocker was added on the basis.1th set of47 patients gather full information, the second group collects complete information on44.3.(1) Before the treatment of231of information collected for statistical analysis, the incidence of by OABSS score statistic BPH/OAB and grouped by age, average IPSS2average statistical average IPSS, IPSS1, and the average value of QOL, average IPSS1and IPSS2compared with average correlation coefficient of OQL. Correlation between statistical comparative tables.(2)For complete treatment of BPH before4weeks after treatment with single factor than guidance of167-2data for analysis, scoring rate before and after treatment in the analysis tables and change rate of QOL-related factors.(3) Single treatment for BPH factor groups and accept the OABSS filter with OAB treatment-resistant drugs used to treat comparative analysis of changes in QOL after6weeksResults:1.231patients with initial treatment of the effects of OAB (urgent micturition score>2, OABSS score>3) and78votes,33.8%percent of patients with BPH.2.167patients on contrast analysis, The table score rates of change before and after four weeks of BPH single factor treatments are OAB-q> POSQ> OABSS> IPSS.3. Correlation statistics of the tables, OABSS with IPSS and PPBC was better, correlation was statistically significant (P<0.05), correlation with QOL (P>0.05) did not show significant; PPBC and QOL related to the highest degree (P<0.05), while IPSS showed low degree of correlation (P>0.05); the OAB-q and IPSS, QOL, PPBC, OABSS showed positive correlation (P<0.05).4. QOL improve QOL change rate in the pure agent in the treatment group at four weeks and six weeks and double-agents treatment group purer agent double-agents, four weeks after treatment for2weeks was6.3±3.4%and31.9±17.1%.Conclusion:1. Higher prevalence of OAB in patients with BPH, this group was33.8%.2. IPSS storage urinary symptoms and QOL is a strong correlation, voiding symptoms and QOL weak, indicating that the storage of urinary symptoms for patients with life distress index greater than voiding symptoms 3.The OAB-q is the most sensitive to changes of treatment. IPSS sensitivity is the least sensitive to changes of treatment. OABSS sensitivity sits between these two. The OAB-q is most suitable for the efficacy evaluation tools used. PPBC and QOL show the strongest correlation. OABSS best in representing the symptoms, PPBC best in representing the harassments of the quality of life, two tables are simple to understand and in better compliance.4. OABSS plays a guiding role for the initial treatment of BPH. The recommended initial treatment of BPH in patients the application OABSS patients screened and of BPH/OAB patients for targeted treatment.
Keywords/Search Tags:BPH, LUTS, OAB, IPSS, OAB Symptom Survey Score Table
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