Clinicopathological Analysis Of Colorectal Polyps

ObjectiveTo explore the clinical and pathological characteristics of colorectal polyps, and analyze the related factors of polyp canceration.MethodsThe complete information of772subjects diagnosed with colorectal polyps who were found by colonoscopy was from the Second Affiliated Hospital of Zhengzhou University. I divided all the subjects into adenomatous polyp group and non-adenomatous polyp group and made a comparison for their clinical features. After eliminating28cases with malignant transformation, according to the latest American diagnostic criteria for high-risk adenomatous polyps, I divided the subjects diagnosed with colorectal adenomatous polyps into high-risk group and low-risk group and made a comparison for their clinical features. Analyze the relationship between the size, shape and pathological types of the colorectal polyps and canceration.ResultsColorectal polyps were found in different age groups and had male susceptibility (p>0.05). Hemafecia was the most common clinical symptoms and patients with juvenile polyps had the highest incidence of94.4%for hemafecia. Adenomatous polyps and inflammatory polyps predominated in different pathological types of colorectal polyps. The incidence of adenomatous polyps gradually increased with increasing age. The non-adenomatous polyps were more frequently seen in the younger(<60years old) patients(62.7%). There were significant differences for adenomatous and non-adenomatous polyps in shape features, size, atypical hyperplasia and malignant transformation (p<0.05), which both had male susceptibility and were mainly distributed in the left hemicolon. The polyps less than1cm in diameter predominated regardless of adenomatous(82.9%) or non-adenomatous polyps(73.9%). Adenomatous polyps had a higher rate of24.6%for atypical hyperplasia and malignant transformation, whereas, non-adenomatous polyps had a lower rate of3.1%for low-grade atypical hyperplasia, in which no moderate and severe dysplasia as well as malignant transformation were found.Colorectal high-risk adenomatous polyps and low-risk adenomatous polyps had no significant difference in age onset and sex (p>0.05) but not in location (p<0.05). The distribution of the left hemicolon predominated in both the two groups, however, the distribution of the right hemicolon predominated in the low-risk group compared with the high-risk group and the incidence of being located in the total colon was higher in the high-risk group compared with the low-risk group.The canceration rate of colorectal polyps increased with the increasing of the size. The polyps than2.0cm in diameter had the highest(57.4%) canceration rate. The canceration rate of lobulated polyps was significantly higher than non-lobulated polyps. The canceration rate of villous adenomas reached31.3%, the highest in the three types of adenomatous polyps.ConclusionsDifferent types of colorectal polyps vary on clinical features. To master these features can make for making a preliminary judgment on the nature and risk stratification of polyps during a colonoscopy. It also defmitudes the necessity of valuing predilection site, careful exploration of the entire colon and endoscopic treatment for the crowd of different ages and gender. Being>2.0cm in diameter, lobulated, high hair ingredients of adenomatous polyps are the high risk factors of colorectal polyp canceration.