Execuitve Functions In The Paitents With Primary Insomnia: A Case-Control Study

Background Patients with chronic insomnia often claims reduced ability of workand adapt, but objectively damage and its extent has not been fully understood.Executive function(EF) is to reflect the individual’s integration of information, tooptimize output and problem-solving and compared with memory, attention and otherbasic cognitive function,it is more closer to individual ability of work and adapt,more suitable for an objective assessment. The previous objective assessment of theexecutive function of patients with chronic insomnia is inconclusive. It does notdistinguish between primary insomnia (PI) and other types of insomnia(for example,Comorbid insomnia),small sample size may be related to these studies, a singleexecutive function tests selected and the differences of results is large and efficiencyis not high, Therefore, further validation studies need the improvement of themethodology. Behavioral Assessment of the Dysexecutive Syndrome (BADS) is anew kind of executive function measurement method and has the advantages ofsystematic and higher eco-efficiency, and it has been widely used in clinicalassessment. In this study used the BADS survey PI patients’s executive function inorder to assess the effects of executive function of chronic insomniaObjective Study of primary insomnia whether exhibit impaired executive functionand its possible influencing factors.Methods Measuring30PI patients and32healthy controls for executive function by BADS. Furthermore, four Scales (HAMD-17, AIS, ESS, MoCA) was used toexplore the effect of relevant variables.Results The PI group and control group in BADS total score (t=-1.70, P=0.10),rule shift cards test (t=-0.95, P=0.35), action program test (t=0.72, P=0.47),temporal judgment test (t=0.74, P=0.46), zoo map test (t=-1.50, P=0.14) andmodified six elements test (t=-0.36, P=0.72) are no significant difference, while thePI group for key search test (t=-2.51, P=0.015) lower than the control group. BADStotal scores of PI patients correlated with anxiety symptom levels (r=-0.38, P=0.003) and MoCA score (r=0.21, P=0.044).Conclusion Comparing PI patients with healthy subjects the performance ofexecutive function show no remarkable impairment, but at the high cognitive loadtasks such as problem solving, there was differences. Performance of executivefunction of PI patients is impacted by anxiety and general cognitive level.