| The ultimate outcome of a variety of renal disease progression of chronic renal failure, is one of the common clinical incurable diseases. Under the guidance of Zhengji theory, giving full consideration to disease. Certificate Hou, symptoms of Chronic Kidney disease3-5period is of great significance to improve symptoms, slow down the speed of progression to renal failure and improve patient quality of life.The thesis includes two parts, literature review and clinical studies.Literature review on the understanding of Chinese medicine for Chronic Kidney disease3-5period, including the name of disease, etiology and pathogenesis, treatment of Chinese medicine, Western medicine study on Chronic Kidney disease3-5period, shenluozhengji theory discussed, including the formation of Shenluozhengji theory, Chinese medicine pathogenesis and TCM treatments.The clinical research section, it is a clinical research of Qi and phlegm, TongluoXiaoji treatment of3-5chronic kidney disease. Objective: through observation and treatment before and after the TCM syndromes integral changes as well as BUN and Scr eGFR to assess the Qi and phlegm, Tongluoxiaoji the clinical efficacy of integrated treatment of circulation and relief of Chronic Kidney disease3-5. Methods:The control group of60cases, to the Western basic treatment plus TCM treatment. The treatment group of162patients, to the Western basic therapy plus treatment of Chinese medicine by disease dialectical debate disorder Fang Qi and phlegm, meridians consumer product. Observe the changes of clinical symptoms of change and of BUN, Scr in eGFR of change. Results:1, treatment group, the total effective rate was82.1%, control group cl inical total effective rate was53.3%, two sets of comprehensive therapeutic effect was highly significant difference (P<0.01), the treatment group than the control group.2After treatment, Scr and BUN with eGFR compared statistically different (P <0.05);the control group before and after treatment, Scr and BUN and eGFR was no significant difference (P>0.05); Scr and BUN and eGFR and treatment in the treatment group, compared with a high degree of statistical significance (P <0.01).3, two groups of TCM Hou total effects, total effective rate was80.2%, and60%in the control group respectively, there were significant differences (P<0.01). Treatment group than the control group to improve the TCM syndrome Hou.4, before and after treatment, malaise and fatigue, shortness of breath, disinclination to talk, eat less poor appetite, irritability, mouth pain, mouth sticky, clear long nocturia, weak waist, stool viscosity, nausea, vomiting has significant The difference in differences (P<0.05or P<0.01).Conclusion: Western basis of treatment with Qi and phlegm, Tongluoxiaoji to treat Chronic Kidney disease3-5in patients with basic addition and subtraction, can significantly improve the clinical symptoms, in particular, is particularly suitable for hot and humid for qi deficiency and cholestasis. Also a significant increase in eGFR and lower Scr, BUN, improve renal function. |
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