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Musk, Invigorate The Circulation Of Scattered Prevention And Treatment Of Femoral Fractures Of Lower Extremity Deep Venous Thrombosis After Clinical Studies

Posted on:2013-08-04Degree:MasterType:Thesis
Country:ChinaCandidate:Q LiFull Text:PDF
GTID:2244330395479159Subject:Orthopedics scientific
Abstract/Summary:PDF Full Text Request
Purpose:To investigate she xiang huo xue san in the prevention and treatmentof femur fractures after surgery due to deep venous thrombosis, clinicalefficacy, safety, and its mechanism of action. Observed she xiang huo xue sanindex changes femur fracture surgery hemorheology, prothrombin time (PT) andactivated partial thromboplastin enzyme time (APTT). I hope to show that theseindicators improves blood Tablets promote blood circulation, improve bloodhyperviscosity, hypercoagulable state. Lower femur fracture after deep veinthrombosis (DVT) risk factors in order to reduce its incidence.Material and method:There are50cases from January2010to March2011, FushunCity Hospital orthopedic ward routine femoral fracture patients hospitalizedqualified cases classified into A, B, after12hours were given she xiang huoxue san, low molecular weight heparin calcium intervention, treatment lasted10days. Observed three groups of patients with surgery, postoperative l14days of blood rheology, PT and APTT index changes. And compare the two groupof patients the incidence of DVT.Results:1.hemorheologyThe results show that the medication for two groups of hemorheology inpatients with no significant difference (P>0.05). The two groups of patientswith preoperative and postoperative day1Comparison of ESR was significantlyhigher, statistically significant (P <0.05). The rest of hemorheology Althoughthere is no statistical difference, but most of the first postoperative dayhemorheology mean lower than the preoperative14th day of whole blood viscosity,whole blood high shear relative to the index, low shear whole blood relativeto the index, the low-shear reduced viscosity of the whole blood, whole bloodhigh shear reduced viscosity decreased significantly (P <0.05). Thehemorheology than group B patients in group A after treatment. Plasma viscosity index in group A and group B a significant difference (P <0.05).2.coagulation group seized indicatorsThe study results show that the medication the first three groups of patientswith PT and APTT showed no significant difference (P>0.05). Three groupsof patients with preoperative and postoperative day1Comparison of PT indexa significant difference (P <0.05) of APTT was no significant difference (P>0.05). In the preoperative and postoperative first14days itself PT andAPTT indicators were statistically significant (P <0.05). A group and B groupPT There was significant difference (P=<0.05) and APTT was no significantdifference (P>0.05).3.DVT the occurrence rateThe results showed that50cases, a total of three cases of DVT, the overallincidence rate of4%. Group A, two cases of DVT, the incidence of8%. GroupB occurred one cases of DVT, the incidence was4%Conclusion:She xiang huo xue san and low molecular weight heparin for most ofhemorheology showed significant improvement in plasma viscosity improvement,she xiang huo xue san as low molecular weight heparin. At the same time shexiang huo xue san and low molecular weight heparin can be significantlyprolonged PT and APTT, but the low molecular weight heparin is better than muskblood scattered. So she xiang huo xue san intervention femur fracture surgerypatients, can reduce the patient’s blood rheology and the extension of thecoagulation group seized indicators, to improve blood hyperviscosity,hypercoagulable state. In terms of safety, postoperative she xiang huo xuesan than the low molecular weight heparin caused less bleeding, and cansignificantly reduce the postoperative bleeding tendency, there is bettersecurity...
Keywords/Search Tags:femur fracture surgery, deep venous thrombosis, she xiang huo xuesan, hemorheology, coagulation index group seized
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