| Non-alcoholic fatty liver disease (NAFLD) is a common liver disease, liver fat deposition transition over the liver wet weight of5%to10%of a series of clinical and pathological syndrome. Simple steatosis (simple fatty liver, SFL), non-alcoholic steatohepatitis (non-alcoholic steatohepatitis, NASH) and its related cirrhosis. NAFLD can directly lead to decompensated cirrhosis, hepatocellular carcinoma and liver transplant recurrence, can also affect the progress of other chronic liver disease, and to participate in the incidence of type2diabetes and atherosclerosis. To this end, NAFLD is the new challenges of the contemporary field of medicine, will be a continuing increase in the near future NAFLD harm to human health.Western medicine in the treatment of non-alcoholic fatty liver disease is still the lipid-lowering drug-based treatment of fatty liver, Western medicine is still no cure for the prevention and treatment of fatty liver, even if Western insisted that its side effects are very small, but in the case of unknown pathogenesis, treatmentthere is a clear liver and kidney damage or gastrointestinal reactions and other side effects, and long-term large number of clinical cases also proved the existence of significant side effects. With the development of medical science and the depth of people’s understanding of the overall concept and the idea of the diagnosis and treatment of Chinese medicine in the treatment of fatty liver has increasingly shown its unique people-oriented, fundamentally grasp the the patients etiology and pathogenesis. syndrome differentiation given individual treatment programs, to fundamentally change the body type, get rid of the disease, showing its incomparable superiority.This issue is access to a large number of clinical data and literature on the basis of each node summed stagnation and spleen deficiency Phlegm lead to non-alcoholic fatty liver disease is the most common pathological basis, throughout the whole story, so simple fatty liver can give Shuganstagnation,spleen qi. wet phlegm, blood circulation for the basic rules for treatment and observation.The main subject of observation pricking spilled blood therapy for the treatment of liver spleen phlegm and blood stasis each node type of simple fatty liver disease in clinical efficacy.The paper mainly by the literature review section and clinical research component.The literature review part of a total of two,the first non-alcoholic fatty liver disease etiology and pathology of modern research profile, from the perspective of Western medicine into decades of non-alcoholic fatty liver disease etiology and pathology of modern research profile a summary of the liver sleatosis,insulin resistance and nonalcoholic fatty liver disease etiology and pathology that should be based on the pathogenesis of the different people of different therapies. Second from the phlegm and blood stasis treatment of non-alcoholic fatty liver disease, medical advances, summed up into decades of literature and clinical data, from a medical point of view to analyze its etiology and pathogenesis, investigate the treatment. Chinese medicine, non-alcoholic fatty liver disease to liver Yu. spleen pathogenesis. the phlegm and became pathological product, liver and spleen, phlegm and blood rule of law, for diagnosis and treatment, to develop individualized treatment approach. Objective: through a large number of pricking blood therapy, a small amount of pricking blood therapy, oral Xuezhikang treatment of non-alcoholic fatty liver disease, they were randomly divided into three groups were compared clinical efficacy, to explore a more suitable non-alcoholic fatty liver diseasetreatment. Methods:104diagnosed with moderate to severe in patients with nonalcoholic fatty liver, the TCM disease is liver depression and spleen phlegm and blood stasis type, a large number of Bloodletting group of35patients were randomly divided into treatment order, a small amount of Bloodletting33patients, the drug treatment group of36patients. Three groups to receive basic treatment, while at the same time, a large number of Bloodletting group the Ze-foot Ququan, Qu Ze, the appointment of Yang. Zusanli. Yin Ling Quan, Hong Leong points to take four points for the treatment of a large number of pricking spilled blood; a small amount of Bloodletting group also select four points in the above few points shallow thorn spilled blood therapy; drug group was given oral Xuezhikang0.6g, sooner or later1treatment. Observed before and after treatment of B-TG, TC,total efficacy of TCM symptoms, symptom scores and other indicators of changes recorded adverse reactions and safety testing, statistical analysis of the clinical efficacy and safety. Results: The three groups of patients with clinical general information (gender, age, body mass index, duration) there was no significant difference (P>0.05). comparable; Bloodletting group clinical efficacy total effective rate was91.43%, a small amount of Bloodletting group was72.72%, the drug group was77.78%. a large number of Bloodletting group more effective than the drug group (P<0.05). a small amount of Bloodletting and drug efficacy (P>0.05). Fatty liver B-ultrasound imaging can be seen a large number of pricking blood therapy and drug therapy can significantly improve fatty liver, and significantly reduced TG, TC level, where a large number of Bloodletting group drop TG, TC’s significantly better than a small amount of Bloodletting group and drug group (P <0.05). to improve the efficacy of B-ultrasound imaging was significantly better than a small amount of pricking blood group and drug (P <0.05). The course of the study no serious adverse reactions in addition to gastrointestinal discomfort,blood, urine, liver and kidney function before and after treatment were no obvious abnormalities. Conclusion: pricking spilled blood therapy is the treatment of liver spleen phlegm and blood stasis each node type of non-alcoholic fatty liver disease (simple fatty liver) an effective and safe method, should be widely applied. |
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