| Objective To analyze the Chinese medicine (CM) syndrome pattern of146patients with diabetic peripheral neuropathy and discuss the characteristics of various Chinese medicine (CM) syndrome patterns and the relationships with course of DM disease, blood glucose, nerve conduction velocity as well as the incidences of other diabetic chronic complications.Methods The basic information, C M syndromes, tongue and pulse, blood glucose, the incidences of other diabetic chronic complications of146cases of hospitalized patients with diabetic peripheral neuropathy in Guanganmen and auxiliary examination data were recorded. Through CM syndrome patterns bianzheng after statistics,4main patterns including A. yin-deficiency with exuberant heat pattern; B. Piqi deficiency with damp-heat syndrome pattern; C, both qiyin deficiency pattern; D. both yin-yang deficiency pattern and one concurrent or accompanied excessive syndrome-blood stasis were concluded, and the characteristics of various Chinese medicine (CM) syndrome patterns, incidence rate of blood stasis, course of DM disease, blood glucose control, nerve conduction velocity and the relation with other diabetic chronic complications were discussed.Results The CM syndrome patterns commonly encountered in mostly of the146patients was pattern D (89patients,60.96%); the next was pattern C (45patients,30.82%) and pattern A(6patients,4.11%) and pattern B (5patients,3.42%); while the accidence of concurrent or accompanied excessive syndrome-blood stasis reached90.41%(132patients); various CM syndrome patterns with blood stasis:the incidence rate of blood stasis of pattern A was100.00%, pattern B was80.00%, pattern C was86.96%, pattern D was92.13%, with no statistically significant difference of incidence rate of blood stasis among all the patterns (P>0.05).Comparing the course of DM disease of all CM syndrome patterns, there was statistically significant difference P<0.05;the course of disease of pattern D was the longest, with11.72±6.53years, the next was pattern C, with8.24+5.39years, and pattern B and pattern A were relatively short, with5.41±6.18years and 5.00±3.69years, respectively. The tendency chart showed the course of DM disease was positively correlative with CM syndrome patterns. The difference of FPG, HbA1c of all CM syndrome patterns was not statistically significant, but the mean FPG and HbA1c level of all the patterns with DPN was relatively high; HbA1c level of pattern B was higher than pattern A, pattern C and pattern D. The incidence rate of all other diabetic chronic complications of all CM syndrome patterns had no statistically significant difference (P>0.05); the tendency chart of incidence rate of complications of all CM syndrome patterns showed:the incidence rates of other diabetic chronic complications of pattern A and D were relatively high. Duration of0-5years group6-10years group,11-15-year group, over16years,4course of group movement ulnar nerve, median nerve, tibial nerve conduction velocity were significantly different (P<0.05), whichmotion ulnar nerve and median nerve P<0.01, and nerve conduction velocity in diabetic showed a decreasing trend; across the disease group movement peroneal nerve conduction velocity was no significant difference (P>0.05), but the nerve conduction velocity with the extension of the course wasdecreasing trend; across the disease groups feel the ulnar nerve, median nerve, the superficial tibial nerve conduction velocity were significant differences (P <0.05), and decreased with the nerve conduction velocity in diabetic; across the disease groups feel sural nerve conduction velocity differencesnot statistically significant (P>0.05), but the nerve conduction velocity showed a decreasing trend with the extension of the course.Conclusions The CM syndrome patterns commonly encountered in most of the patients with diabetic peripheral neuropathy was pattern D, and the next was pattern C, and the incidence of A and B was relatively low, and most patients with diabetic peripheral neuropathy had blood stasis; The CM syndrome patterns commonly encountered mostly in the early course of DM disease were pattern A and pattern B, with relatively few other diabetic chronic complications, in the middle course of disease, pattern C and pattern D, gradually with various other diabetic chronic complications, peripheral nerve conduction velocity gradually reduced; in the late course of disease, was pattern D, with various other diabetic chronic complications, peripheral nerve conduction velocity to reduce significantly; the blood glucose control of all CM syndrome patterns is poor. |
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