The Research Of Physical Training Security Situation And Strategy In The Independent Colleges Of Hunan Universities

Nitric oxide (NO) radical is a small molecule gas, of which we do not have aclear understanding of the biological function in the past. The research of nitric oxideradicals has been entered into a new era since it is discovered that the chemical natureof a kind of endothelium-derived relaxing factor (EFRF) is nitric oxide radical. Inrecent decades, the research progress on the nitric oxide radicals affects theunderstanding of the nature of a lot of live activities, involving many disciplines,including medicine and pharmacy etc., even extending to the sports disciplines inrecent years. The research about the effect of different exercise load on nitric oxideand nitric oxide synthase has become of the hot aspects. Experts from differentresearch aspects all put efforts into the study of nitric oxide, trying to reveal themysteries of nitric oxide from various angles. Although sports medicine experts havedone a lot of work on nitric oxide, sports and skeletal muscle, there are still manycontroversial issues. In regards to study of the relation of three subtypes of NOS andexercise, there is no a conclusion yet and quite controversy. Existing studies haveshown that exercises lead to NO, NOS activity changes, but the specific subtypesproduced from increased NOS activity caused by exhaustive exercises are unclear.Besides, studies indicate that skeletal muscles contain a large number of nNOS.Therefore, the study speculates that, the reason exhaustive exercises cause increasedskeletal muscle NOS activity is mainly due to the increased nNOS activity.Methods:32rats were randomly divided into control group (Group C) andtraining group (Group E), conducting treadmill exhaustive exercises and samplingimmediately after exercises.Results:(1) After the exhaustive training, the serum CK activity of the rat has increasedby33.81%(P <0.05), serum LDH decreased by7.59%, no significant difference ((P>0.05).(2) After the exhaustive training, the serum NO of the rat has significantlyincreased by16%(P <0.05).(3) After the exhaustive training, the content of MDA in the rat’s skeletal musclehas significantly increased by (P <0.01) and skeletal muscle SOD activity hassignificantly decreased (P <0.05). (4) After the exhaustive training, the NOS activity in total has increased withsignificantly difference. The nNOS activity of the rat’s skeletal muscle hassignificantly increased (P <0.01). The iNOS activity has increased without significantdifference.Conclusion:The exhaustive exercises lead to the increase in serum CK activity.The exhaustive exercises lead to the increase in NOS activity. Its source is theincrease in nNOS activity without the change of iNOS. Due to NOS activity increased,production of NO has also increased.The exhaustive exercises lead to the strengthening of lipid peroxidation.