Clinical Investigation On Canine Chronic Renal Failure In Hohhot

Canine Chronic renal failure (CRF) is clinically characterized by the development of variably progressive irreversible interregnal lesions and loss of renal functions.30cases of canine chronic renal failure during2011-2012in Hohhot area were collected in this investigation, and their background informations were obtained by investigation of case history and clinical symptoms examination individually. Blood and urine interrelated indexes of chronic renal failure in canines were analyzed. Some indexes changes after and before treatment were compared.The dogs with CRF in Hohhot mainly crossbreed canine and their ages were mostly ranged from7to9years old. Most of the cases were the dogs fed mainly with homemade diet, and the dogs over middle ages suffering from CRF were in higher risk.There no significant differences in gender but it mostly attacked in spring and summer seasons. Decreased renal function and increased serum creatinine, usea nitrogen and phosphorus concentration in serum were detected in all canines with chronic renal failure. And decreased concentration of K+, Na+and pH values were detected in most of CRF dogs. The RBC and HGB were decreased in diseased dogs. The urine specific gravity of all caseswere decreased and proteinuria were occurred in some cases. Under radiographic and ultrasonographyic examinations, the sizes of kidney were become larger, smaller or normal, and kidney echo were enhanced.Most indexes ralated with renal functionns of CRF cases were improved after treatment (P<0.01), expect that of urine specific gravity..Most of canines were in the stage of3or4in renal failure and had severe azotemia.Disturbance of acid-base and electrolyte balances,decreased urine specific gravity and proteinuria.Canines with CRF significantly improved after treatmented.However most cases were came to clinic too late,so lead the prognosis is poor usually.