Font Size: a A A

Effect Of Gln-RIP On The Digestion And Absorption Of Small Intestine Of SD Renewal Rats Without Colostrums

Posted on:2014-09-26Degree:MasterType:Thesis
Country:ChinaCandidate:M J TaoFull Text:PDF
GTID:2253330425452754Subject:Basic veterinary science
Abstract/Summary:PDF Full Text Request
In this paper, Gln-RIP of exogenous is used to testing administrated with different doses ofGln-RIP to SD renewal rats,and used the Anatomy Technology,ImmunohistochemistryTechnology,Hematoxylin-Eosin Stain and D-xylose Absorption Test methods to detect thedevelopment of small intestine,the quantities both of epidermal growth factor and somatostatinpositive cells in the small intestine,On the different of test group digestion and absorptionfunction of small intestine periods regular,In order to study that Effect of Glutamine on thedigestion and absorption of small intestine of SD renewal rats without colostrums.Which is greenand no adverse effect.Then,provide theoretical basis for the development of the bargain,nonpersistent Glutamine as Agent-Emulsion of SD renewal rats without colostrums.The results showed that:(1) The effect of Gln-RIP on the body weight and the small intestinal weight of SD renewal ratswithout colostrums.0-7days of age,the effect was not significant.14-21days of age,It couldadd body weight and the small intestinal weight of the without colostrums renewal ratssignificantly.(2) It could promote the morphological development to the small intestine of the SD withoutcolostrums renewal rats.It could enlarge the villi height of the small intestine,lower the cryptdepth of the small intestine and increase the value of V/C.The doses of Gln having the best effecton villi height,crypt depth,Value of V/C were increased by the days.(3) It could be promote the development,differentiation,D-xylose Absorption performance to thesmall intestine mucosa were increased by the days.(4) It could increase the quantities of EGF positive cells in the small intestine of the SD withoutcolostrums renewal rats.In terms of somatostatin,it could be repressed D-cells secrets in the smallintestine.The doses of Gln having the best effect on the quantities of EGF positive cells in everyintestine segments mucosa were increased by the day. To sum up, By means supplementation of exogenous Gln-RIP able to intestine mucosa cellsoffering essential energy of metabolism,and could be able to added the body weight,smallintestine weight and merocrine secretion of epidermal growth factor,then reduced SS secrets,Notonly could be promoted regeneration and repair of intestine mucosa epithelial cells.It couldenlarge the villi height of the small intestine,lower the crypt depth of the small intestine andincrease the value of V/C.Not only be able to maintained integrity of mucosal structure,but whileit can be improved active absorption function of renewal rats of SD without colostrums....
Keywords/Search Tags:Radix Isatidia Polysaccharide (RIP), Glutamine(GLN), Hematoxylin-Eosin, Intestinal Morphology, Intestinal Absorption, Epidermal Growth Factor, Somatostatin, Immunohistochemistry, D-xylose Absorption Test
PDF Full Text Request
Related items