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Therapy Of Laryngeal Carcinoma Postoperative Recurrence

Posted on:2013-03-19Degree:MasterType:Thesis
Country:ChinaCandidate:M Y WangFull Text:PDF
GTID:2254330398486143Subject:Otorhinolaryngology
Abstract/Summary:PDF Full Text Request
Objective:To investigate the therapeutic effect of recurrent postoperativelaryngeal cancer.Methods:A retrospective analysis of dalian medical university affilicated firsthospital otolaryngology department since the1998-2009years were742cases ofpatients with laryngeal cancer45patients with recurrent the patient’s clinical data.Which type of recurrent laryngeal29), published on14cases of recurrent type, type2cases across the subglottic recurrence; Local recurrence22cases, neck recurrence in15cases,8cases of distant metastasis. All cases were followed up. Kaplan-Meier isapplicated to perform survival analysis.Results:Patients with recurrent laryngeal carcinoma surgery parts including localrecurrence and distant metastasis and recurrence neck; Throat squamous cell carcinomaof the recurrence time is3-119months and the median time for18months,postoperative recurrence29patients a year, two years recurrence after11cases, threeyears after recurrence in5patients, and the material of the recurrent time characteristicsand domestic material consistent; Kaplan-Meier method for the survival analysis resultsshow that the throat cancer recurrence laryngostenosis after surgical treatment of totalsave3,5years involving the survival rates were46.7%and17.8%respectively, therecurrence rate was6.1%, lower than the domestic data, the result with my families insome patients with radiotherapy after the treatment.Conclusions:Laryngostenosis after a year is the most frequent recurrence,attention should be paid to the surgical appropriate choice and correct treatment ofcervical lymph node metastases, should be closely related to clinical follow-up, regularline imaging examination, strive to early detection of recurrent focal, timely to throatcancer recurrence surgical save surgery, so as to achieve a good curative effect, thisgroup of3years of survival rate can reach46.7%; Local recurrence of the kitchen in the throat resection operation method is given priority to, the neck recurrence in order toenlarge radical neck dissections Lord; The cancer recurrence was deep throat focal andthe organization invasion, surgical, tissue defect much, often needs to be repaired,prognosis is poor. For late recurrence and do not cancer surgery person, can withradiation, chemical treatment and other treatment; To invade and esophagus, influencethe consumption of the patients can do colostomy stomach surgery as early as possible,so that this kind of terminally ill patients survival with tumor can access to certainsurvival time.
Keywords/Search Tags:Laryngeal neoplasms, Laryngectomy, Neoplasm recurrence, Salvagetherapy, Prognosis
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