Resistant Hypertension And Insulin Resistance Related Factors Clinical Research

Objective：To investigate between resistant hypertension and insulin resistancerelated factor of relations.Methods：In2011January to2012January,in the Fifth AffiliatedHospital of Xinjiang Medical University inpatient and outpatient.To compare fastingblood glucose（FBG）,fasting insulin(FINS) and c-peptide,in simple resistant hypertensionpatients (group A)48cases,resistant hypertension combined with type2diabetes mellituspatients(group B)42cases and essential hypertension patients(group C)50case bycase-control study,at the same time determine,body mass index（BMI） triglyceride(TC),total cholesterol(TG),low density lipoprotein cholesterol (LDL-C),and high densitylipoprotein cholesterol(HDL-C) correlation of insulin resistance.Results:(1)Fasting bloodglucose（FBG）,Fasting insulin(FINS) and c-peptide levels of group B were increases ingroup A(P <0.05);(2)Body mass index（BMI） Triglyceride (TC),total cholesterol (TG) ofgroup B were higher than those of group A(P<0.05),low density lipoproteincholesterol(LDL-C) was no significant change;While high-density lipoprotein cholesterol(HDL-C) was lower than group A (P<0.01).By correlation analysis, insulin resistance andbody mass index （BMI）,Triglyceride (TC) and total cholesterol(TG) correlatednegatitvely,positively correlated with high-density lipoprotein cholesterol (HDL-C),but nocorrelated with.low density lipoprotein cholesterol(LDL-C).Conclusions： Resistanthypertension patients combine with type2diabetes existing hyperinsulinemia and insulinresistance compare with simple resistant hypertension more significant.Dyslipidemia andinsulin resistance exist relevance.