The Analysis On The Perimenopausal Syndrome （PMS）Patients’TCM Syndrome Type And The Correlation Of Serum FSH, LH, E₂and Related Factors

ObjectiveTo discuss perimenopausal syndrome (PMS) patients’ TCM syndrome type and and the correlation of serum FSH, LH, E2and related factors,summarizes the general rules,so as to provide an objective reference for the clinical syndrome differentiation and treatment.MethodAccording to the clinical manifestations of patients with perimenopausal syndrome, and refer to the " Differentiation Standard of TCM Syndrome "," gynecology of traditional Chinese medicine"(The Seventh Edition),"diagnostics of traditional Chinese medicine"(The Fifth Edition). Design PMS patients questionnaires, in line with criteria of PMS patients carried on the questionnaire survey, record patients’menstruation, systemic symptom, tongue, pulse condition, according to the TCM diagnosis standard symptoms on syndrome differentiation and classification. Determination of follicle stimulating hormone, luteinizing hormone, blood estradiol by immunofluorescent automatic chemical analysis method. Entry and check the datas, then set up date base by the microsoft excel,The dates used for statistical Frequency analysis, Kruskal-Wallis H test, one-way ANOVA analysis by the SPSS17.0software, and obtain conclusions from the results of the analysis.Results(1)128PMS patients according to the TCM symptoms Diagnostic Criteria divided into deficiency of liver-yin and kidney-yin syndrome44cases, stagnation of liver-QI syndrome30cases, kidney Yin deficiency syndrome29cases, kidney Yin and Yang two deficiency syndrome15cases,kidney Yang deficiency syndrome10cases. The TCM syndrome types number of128PMS patients in descending order: deficiency of liver-yin and kidney-yin syndrome(34.37%)>stagnation of liver-QI syndrome(23.44%)> kidney Yin deficiency syndrome(22.66%)> kidney Yin and Yang two deficiency syndrome(11.72%)>kidney Yang deficiency syndrome(7.81%).(2) FSH figures:adopt one factor analysis of variance between interblock.The results explained the difference among groups was very significant(P<0.05). The comparison between two two groups explained PMS stagnation of liver-QI syndrome FSH levels were significantly higher than other four syndrome types (P<0.05、P<.01), And the relation of FSH figures among the five groups was liver-QI syndrome> kidney Yang deficiency syndrome> kidney Yin and Yang two deficiency syndrome> the deficiency of liver-yin and kidney-yin syndrome> kidney Yin deficiency syndrome.(3) LH figures:adopt one factor analysis of variance between interblock. The results explained the difference among groups was not statistically significant(P>0.05). The comparison between two two groups explained the LH levels were not significant (P>0.05).(4) E2figures:adopt one factor analysis of variance between interblock. The results explained the difference among groups was very significant(P<0.05). The comparison between two two groups explained PMS kidney Yin and Yang two deficiency syndrome E2figures were significantly lower than kidney Yin deficiency syndrome, stagnation of liver-QI syndrome and deficiency of liver-yin and kidney-yin syndrome (P<0.01).PMS kidney Yang deficiency syndrome E2figures was significantly lower than deficiency of liver-yin and kidney-yin syndrome (P<0.05).And the relation of E2figures among the five groups was the deficiency of kidney Yin and Yang two deficiency syndrome<kidney Yang deficiency syndrome<stagnation of liver-QI syndrome<kidney Yin deficiency syndrome<liver-yin and kidney-yin syndrome.(5) The analytic result about the related nosogenic factors revealed:there were correlations between the TCM syndrome type and the age,the Menopause, the number ofpregnancy, the number of delivery (P<0.05). there were not significant correlations between the TCM syndrome type and occupation, the course of disease(P>0.05). Conclusion1. kidney-deficiency, stagnation of liver-QI are the common etiology and pathogenesis athogenesis of PMS,and the kidney-deficiency is the basic etiology and pathogenesis athogenesis of PMS2.The deficiency of liver-yin and kidney-yin syndrome, tagnation of liver-QI syndrome, kidney Yin deficiency syndrome are common patterns.3. There are correlations between the TCM syndrome type and the age, the Menopause, the number ofpregnancy, the number of delivery, there are not significant correlations between the TCM syndrome type and occupation, the course of disease.4. The serum FSH figures and E2figures of different TCM syndrome type of PMS patients are very significant,the Differences Can provide an objective reference for the clinical syndrome differentiation and treatment.