Clinical Analysis Of Maternal And Perinatal Outcomes In106Cases With Severe Preeclampsia

Objective:This study was designed to investigate the clinical pictures, maternal andneonatal outcomes in patients with severe preeclampsia, as well as the clinical boundaryand the relationship between expectant management and pregnancy outcome in earlyonset patients for further understanding of such entity to guide clinical practice.Methods:The clinical data were retrospectively analyzed in106patients with severepreeclampsia, who were allocated to groups of A28-31+6weeks, n=14), B (32-33+6weeks, n=24) and C (≥34weeks, n=68) by the onset of gestational age. The threegroups of patients were compared regarding the general condition, time of expectantmanagement and the complications for parturients as well as the outcomes ofperineonates.Results:1.The differences were significant in systolic and diastolic blood pressure uponadmission in the three groups of patients (P<0.05);2.In terms of the duration ofexpectant treatment,group A took the longest,while group C the shortest,and the threegroups were significantly different(P<0.05);3.The complications in pregnant women ofGroup A and Group B showed no significant differences(P>0.05),whereas thecomplications in Group C had a remarkable decrease,with significant difference(P <0.01);4.Group C were found to have far lower neonatal asphyxia,fetal distress inuterus,fetal growth restriction, intrauterine death and prenatal mortality as compared with group A and B(P<0.05or P<0.01).The incidence of small-for-date infants declinedgradually with the extension of the onset of gestational age,which had a significantdifference(P<0.01).Conclusions:1.maternal and perinatal outcomes are more bad in gestational ages lessthan34weeks.2.the incidence of gestational age <34weeks of severe preeclampsiamother son end badly.2.Early onset severe preeclampsia pregnant women,less than34weeks, reflect a better picture of correlation between the onset of gestational age andperinatal outcome.3.Clinical study shows that the expantant management can beeffective for the early onset severe pre-eclampsia on condition that we carefully selectstable patients and closely monitor their condition. During the process of expantantmanagement, if the condition was stably controlled and no maternal and Perinatalcomplications appeared, expantant management should not be terminated until the34thweek.