The Influence Of Pregnancy And Delivery Outcome After LEEP Or CKC Conization Of Cervix Treatment

Objective: The aim of this study was to investigate the influence of pregnancy and delivery outcome in obstetrics after LEEP or CKC conization of cervix treatment,providing the basis selection of the treatment method of patients with high levels of cervical disease for gynecologists recommendations.Methods: Retrospective analysis of the cases from 2005 January to 2015 January in the Department of Obstetrics of the Women and Children Hospital of Shenyang,who were treated for pregnancy and delivery problems after conization of cervix treatment due to CIN ?-?.Follow-up to 221 patients,162 eligible cases were selected,including 101 cases of LEEP group and 61 cases of CKC group.Selection criteria: age 20 to 39 years old;no history of repeated abortion;no history of preterm birth and dystocia;according to the wishes of patients choose LEEP or CKC treatment;pathological diagnosis of CIN ? or CIN ?.Exclusion criteria:Patients did not meet the selection criteria;had done the cervical cerclage during pregnancy.At the same time,according to the principle of matching the age and production times of pregnant women,1: 1 collected healthy pregnant women who were hospitalized in the same hospital as control group randomly.Selection criteria: no history of CIN ? or CIN ?;no history of cervical surgery(electrocautery,freezing,laser,LEEP,CKC and so on);no recurrent miscarriage and premature birth history.The two groups and the LEEP or CKC groups were observed and compared with the occurrence rate of abortion,premature,preterm with premature rupture of membrane,low birth weight,the composition of cesarean,to understand the influence of pregnancy and delivery outcome in obstetrics after conization of cervix treatment and the differences between LEEP and CKC.SPSS 20.0 software is selected for statistical analysis.The mean and the standard deviation is selected to express measurement data,Chi square test and continuity corrected chi square test are used to analysis of count data,There were statistically significant differences in P<0.05.Results:1.There was no statistical difference between the case group and the control group in the general situation of pregnant women,such as age,production times,weight gain,marital status.2.The low birth weight infants rate(10.5%),preterm delivery rate(15.4%)and preterm with premature rupture of membrane rate(24.7%)were higher in the case group than in the control group,there was statistical difference between the two groups.But there was no statistical difference in the occurrence rate of abortion(P=0.5156>0.05)and cesarean delivery rate(P=1.0722>0.05).3.The low birth weight infants rate(5%),cesarean delivery rate(80.1%),preterm with premature rupture of membrane rate(18.8%)were lower in the LEEP group than in the CKC group,there was statistical difference between the two groups.But there was no statistical difference in the occurrence rate of abortion(P=0.1106>0.05)and preterm delivery rate(P=0.0666>0.05).Conclusion: 1.Cervical conization does not increase the incidence of miscarriage and the proportion of cesarean delivery.2.Cervical conization can increase the incidence of preterm birth and low birth weight children,and may significantly increase the incidence of premature rupture of membranes.3.LEEP relative to CKC,does not increase the incidence of abortion and preterm birth.4.LEEP relative to CKC,can reduce the incidence of preterm premature rupture of membranes and cesarean section rate,and significantly reduce the incidence of low birth weight children.5.LEEP should be a more appropriate option for young and unborn patients who got the disease of high squamous intraepithelial Lesion with fertility requirements.