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Complete Mesocolic Excision Versus Traditional Resection For Colon Cancer: Meta-analysis

Posted on:2014-03-23Degree:MasterType:Thesis
Country:ChinaCandidate:L ZhangFull Text:PDF
GTID:2254330425954671Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective: To evaluate whether the efficient and safety after CME forcolon cancer, compared with traditional resection. Methods: We searchedthe bibliographic databases in order to identify relevant studies from2008to2013, included randomized controlled (RCT) and non-randomizedconcurrent control trials. We fetched the clinic trials’ characteristics tofinish the META-analysis with the standards for inclusion and exclusion.Results: We confirmed5clinical trials finally. In comparison with thetraditional resection group, the lymph nodes harvest was more than thetraditional resection [IV3.66,95%CI(2.28,5.04),P<0.00001]. And theperioperative bleeding [IV42.22,95%CI(-22.59,107.02),P=0.2]、complication [IV-0.05,95%CI(-0.53,0.42),P=0.82]、time for analexhaust [IV0.28,95%CI(-0.39,0.95),P=0.41]、length of hospital stay[IV0.07,95%CI(-3.01,3.16),P=0.96] has no significant differences inthe rate. Conclusion: The CME can improve the5-year survival, and safe like the traditional resection.
Keywords/Search Tags:Colon cancer, Complete mesocolic excision, CME, Meta-analysis
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