Xuebijing In Severe Trauma Complicated With Multiple Organ Dysfunction Syndrome In The Application Of Comprehensive Evaluation

Objective: At present, using a variety of means for the treatment of MODS, hasmade some progress, but still has a high mortality rate, the high cost of treatment, thefundamental reason is that at this stage can not be effectively inhibited MODSpathological process, although the use of various kinds of advanced methods to prolongthe lives of patients, but after the change is, the higher mortality. The mortalityincreased with the number of organ failure and increases, therefore, to explore a moreeffective prevention and control means to improve the patient’s prognosis and quality oflife has become a focus in the research field of critical disease. Microcirculationdisorder, MODS patients with blood stasis, blood flow is not smooth, is an importantpathophysiological changes, provided the main basis for the Chinese medicineHuoxuehuayu method in treating MODS. This research through the observation ofXuebijing injection in the treatment group and the control group patients clinicaloutcomes, whether explicitly Xuebijing injection can shorten the course of disease inpatients with multiple organ dysfunction syndrome, improve the symptoms, preventorgan dysfunction has further aggravated, protection has not been affected organ andwhether there are significant side effects. Provide a useful reference for the clinicaltreatment of severe trauma complicated with multiple organ dysfunction syndrome.Methods: A multicenter, randomized, parallel controlled method of grouping, onmultiple organ dysfunction caused by acute trauma syndrome were observed. Thetreatment group and the control group were selected for the individualized treatment inpatients with the best, in order to ensure patient safety, ensure that won’t because ofclinical research on patients caused by physical damage. The treatment group in theindividual therapy plus Xuebijing injection, the reaction of the patients who wereobserved after treatment, selection of circulation, respiration, blood system most easily affected in MODS observation index. Circulation: the observation increased meanarterial blood pressure, urine volume whether treatment with Xuebijing injection, heartrate are decreased, as compared with the control group, there was statistical significance;Breathing: To observe the effects of oxygenation index whether elevated, respiratoryfrequency decreased, as compared with the control group, there was statisticalsignificance; Blood: the observation of platelet is increased compared with the controlgroup, there was statistical significance; Synthesis: whether to increase the organ score,as compared with the control group, there was statistical significance.Results: Were evaluated by clinical control, markedly effective, ineffective, death.Xuebijing injection rate reached88.46%group control treatment, the control group thecontrol rate was70.83%, the two groups by statistical comparison, there was asignificant difference, P<0.05.Conclusion: Xuebijing injection, based on the primary disease control, can becaused by multiple organ dysfunction therapy multiple trauma syndrome, breathing,circulation and coagulation were more than the control group had significantimprovement, improve the mean arterial blood pressure, increase urine volume, improveoxygenation, improve coagulation, shorten the course of disease, improve symptoms,prevent the affected organ dysfunction aggravated, protect the uninvolved organs. Noremarkable adverse effect was found in clinical trials.