Analysis Of Clinical Characteristics Of Hashimoto’s Thyroiditis Coexisting With Papillary Thyroid Microcarcinoma

Objection:To investigate differences between patients with Hashimoto’sthyroiditis (HT) coexisting with papillary thyroid microcarcinoma(PTMC) and papillary thyroid microcarcinoma for clinical characteristics.Methods:We collected447cases of papillary thyroid cancer (PTC) thatreceived thyroid surgery and pathologically confirmed in the SecondHospital of Jilin University from January1,2011to December1,2013.245of the total cases were PTMC. There were93confirmed cases ofPTC, including66cases of PTMC, combined HT. Patients’age, sex,thyroid gland ultrasonography, central lymph node metastasis andmulifocality between HT combined PTMC group and pure PTMC groupwere retrospectively reviewed. As well as the effect of tumor size and HTon the presence of central lymph node metastasis was analyzed. Statisticanalysis was performed with SPSS19.0Chinese statistical software.Results:HT combined PTMC group showed a higher proportion of women, alarger average age, the diffuse inhomogeneous echo in more glands, asmaller rate of central lymph node metastasis than pure PTMC group, andthe differences had significant statistical significance. There were nosignificant statistical differences in age composition and mulifocalitybetween the groups above. HT combined PTC group, HT combined PTC(tumor size＞1cm) group and pure PTMC group had smaller rate ofcentral lymph node metastasis than pure PTC group, pure PTC (tumor size＞1cm) group and pure PTC (tumor size＞1cm) group, respectivelyand the difference had statistical significance. There was no statisticalsignificance between HT combined PTMC group and HT combined PTC(tumor size＞1cm) group in central lymph node metastasis.Conclusion:Compared with the pure PTMC group, the HT combined PTMCgroup showed a higher proportion of women, a larger average age, asmaller rate of central lymph node metastasis, and the thyroid glandswere more likely to be diffuse inhomogeneous echo. Pure PTMC grouphad smaller rate of central lymph node metastasis than pure PTC (tumorsize＞1cm) group. When combined HT, PTMC group and PTC (tumorsize＞1cm) group had no statistical difference in central lymph nodemetastasis.