Clinical Reaserch Of Xiaojin Pill Combined With Vitamin E On The Treatment Of Phlegm And Blood Stasis Type Of Mammary Gland Hyperplasia

Breast pain vies with palpable mass as the symptom described most frequently by women presenting to general practitioners or seeking consultation in specialty breast clinics. Which were classified as mammary gland hyperplasia in China. Mammary gland hyperplasia is the most common breast disease,which have a serious impact on women’s health, however, there was no uniform, ideal approach for its treatment and efficacy evaluation, This paper uses Chinese medicine Xiaojin pill combined with Vitamin E to treat the disease, and observe their efficacy. In addition, use the recently introduced VTQ technology to quantify the hardness of breast nodularity And monitor the hardness values changes before and after treatment.Objective:To observe the clinical effect of xiaojin pill combine with vitamin E on the treatment on breast pain and nodules, and to measure the hardness values of breast hyperplasia nodules and observe its changes by using VTQ technology before and after treatment.Methods:Collected from March2013to March2014, General Surgery outpatient60cases of Our hospital, all patients both met the diagnostic criteria of mammary gland hyperplasia, and in line with phlegm and blood stasis of TCM, Other benign breast disease and cancer were excluded, and the duration (?)6months, VAS score (?)4points, the pain days>7days/month, nodularity distribution (?)1quadrant. Patients were randomly divided into A and B group,30cases in each. Group A:Xiaojin pill1.2g/times+Vitamin E capsules,100mg/times, orally,2times/day; Group B:xiaojin Pill,1.2g/times, orally,2times/day for2months, menstruation to stop taking, observe the efficacy and the improvement rates of symptoms (pain and nodules) and the changes of nodules VTQ value after treatment。Results:Into the group of60cases, with no loss, there is no significant difference in Patient’s condition before treatment (P>0.05)(1) Comparison of efficacy:the total effect of group A, pain efficacy, nodules efficacy were (93.3%,96.7%,83.3%), better than the (73.3%,80%,53.3%) of group B, with a significant difference (P=0.038,0.044,0.012);(2) improvement of symptoms:VAS scores, pain scores, nodules (size, hardness, range) integral and systemic symptom scores have a significant difference before and after treatment (P<0.05), Comparison between the two groups With a significant difference (P=0.028,0.022,0.021,0.035,0.033,0.038)(3) breast nodules VTQ value have a significant difference (P<0.05) before and after treatment, Comparison between the two groups was statistically difference (P=0.048).Conclusions:1The effect of Xiaojin pill combine with vitamin E on the treatment of mammary gland hyperplasia is better than single Xiaojin pill, and almost have no side effects.2VTQ technology can quantify the hardness of breast nodularity, can monitor the changes before and after treatment, it is of value on the hardness evaluation of mammary gland hyperplasia, and it could enrich its efficacy evaluation system.