Early Diagnostic Value Of PCT, CRP For Patients With Severe Head Injury Lung Infection

Objective:To investigate the PCT, CRP and other inflammatory markers laboratory test values for lung infection in patients with severe traumatic brain injury early diagnosis.Methods:After selecting direct trauma to live close Critical Care Medicine63patients with severe traumatic brain injury patients, including39males and24females, aged14to85years, mean age (40±4.25) years old. Specimens from ICU admission within1h after blood samples were then collected daily clinical data, record the temperature peak (℃), white blood cell count (WBC) and neutrophils (NEU), acute phase reactive protein (CRP), down calcium original (PCT), combined with microbiological indicators, imaging findings as observed indicators list. All parameter settings and experimental procedures were conducted in strict accordance with the rules. According to the final clinical features and laboratory findings, patients were divided into non-infected group and infected group. All data SPSS13.0statistical software, statistical analysis of measurement data with normal x±s said that two samples were compared using two completely randomized design data mean t-test, test level a=0.05. P<0.05was considered statistically significant. Combined list of indicators discussed above indicators of lung infections in patients with severe traumatic brain injury early diagnosis and treatment of clinical significance.Results:1. Infection detected in serum PCT positive rate97.3%, CRP testing positive rate was100%, PCT, CRP levels were significantly higher than non-infected group, the differences were statistically significant (P<0.05).2. PCT, CRP sensitivity for early diagnosis of pulmonary infections in patients with severe traumatic brain injury were76%,81%, specificity was69%,15%.Conclusion:PCT combined CRP testing positive rate and high specificity, so the joint monitoring of patients with severe traumatic brain injury in serum PCT and CRP levels can be used as ICU patients with severe traumatic brain injury secondary to pulmonary infection more specific and sensitive early indicators.