Correlation Between Anemia And Diabetic Nephropathy

OBJECTIVE:Diabetic nephropathy (Diabetic nephropathy, DN) is a common complication of diabetes (Diabetes mellitus, DM), but also a common cause of clinical end-stage renal disease. The anemia of chronic kidney disease (chronic kidney disease, CKD) is a common complication, we often referred to as renal anemia (Renal Anemia, RA), the high incidence of CKD patients on many aspects of work, life, etc. can be severely affected, and may even accelerate progress CKD deterioration of renal function. A retrospective analysis of the study are summarized contact anemia associated with type2diabetic nephropathy.Methods:60cases of diabetic nephropathy patients from June2013to December2013at the Second Hospital of Lanzhou University hospital of type2, in which32males,28females, aged37-68years old were treated, mean age (53±0.5years), diabetes duration4-20years, with an average duration (11.3years) as a study group. Select the corresponding period in patients with type2diabetes admitted to hospital without60patients with impaired renal function as a control group of patients to collect personal data, fasting blood glucose (FPG),2h postprandial blood glucose (2hPG), glycated hemoglobin (HbA1C), urinary albumin, C-peptide, TC, TG, HDL, LDL, C-reactive protein (CRP),24h urinary albumin and blood, red blood cell (RBC), hemoglobin (HGB), urea (BUN), creatinine (CREA) measurement and measuring glomerular filtration rate (GFR). Anemia in patients with severe anemia in three further lines, prothrombin time (PT), activated partial thromboplastin time (APTT), D-2dimer (Dimer) and other related measurement. Comparative analysis of the incidence of anemia, and further consolidation of anemia in patients with diabetic nephropathy in HbA1C and without anemia in patients with HbA1C comparison group to explore the impact of anemia on HbA1C measurement and guidance for clinical practice.Results:1and without renal dysfunction in type2diabetes compared with the control group, diabetic nephropathy patients more likely to merge anemia, the difference was statistically significant (P<0.05).2diabetic nephropathy patients with anemia after their glycated hemoglobin (HbA1c) measurement value is lower than patients without anemia, measured by HbA1c effects of anemia.Conclusions:In patients with type2diabetic nephropathy population, the prevalence of anemia was significantly higher than non-diabetic patients with nephropathy. And when patients with anemia, glycosylated hemoglobin (HbA1c) values can not be a true reflection of the determination of the patient’s blood sugar levels can not be used as indicators for monitoring the condition of observation and efficacy. The anemia will deteriorate further aggravate the progress of CKD, seriously affecting the quality of life of diabetic patients, and therefore, the need for such patients as early as possible the relevant checks, timely diagnosis and treatment.