Detection And Analysis Of Immune Antibodity Level Of Three Compulsory Vaccination Viral Diseases In Scale Pig Farms Of A County In Baoji Area From2011to2013

Classical swine fever (CSF), Foot-and-mouth disease (FMD) and highly pathogenicporcine reproductive and respiratory syndrome (PRRS) are classified as type “A” diseases byChinese government. A compulsory immunization policy is taken in the pig population forcontrolling and preventing these three important infectious diseases for ensuring the safety ofthe pig industry in China. The immunized pigs stimulate production of antibodies against aninfectious agent invasion and infection. The vaccine antibody detection is an importantroutine in big scale pig farm for evaluating the immunization effect. A high titer neutralizingantibody of special vaccine is expected in preventing and controlling the infectious diseasesin pig.In this study, the immune antibody of CSF, HP-PRRS and FMD were detected enzymelinked immunosorbent assay (ELISA) in pigs vaccinated with CSF, HP-PRRS and FMDvaccines, respectively. Total1035sera were collected in fattening pigs in50big scale pigfarms from2011-2013in Bao-ji district of Shaanxi province, China. The results will providea basic data for preventing, controlling and purifying those infectious diseases, such as CSF,HP-PRRS and FMD in this district. The results as following:(1) Large-scale pig farms (Number of slaughter pigs/year≥10000): The immuneantibody of CSF were92.4%,95.8%and98.0%up-to-standard in2011,2012and2013,respectively; the immune antibody of FMD were91.4%,92.6%and94.0%up-to-standardin2011,2012and2013, respectively; the immune antibody of PRRS were88.6%,87.4%and91.0%up-to-standard in2011,2012and2013, respectively.(2) Medium-scale pig farms (3000≤Number of slaughter pigs/year <10000): Theimmune antibody of CSF were84.6%,90.7%and93.0%up-to-standard in2011,2012and2013, respectively; the immune antibody of FMD were83.1%,88.0%and87.8%up-to-standard in2011,2012and2013, respectively; the immune antibody of PRRS were76.9%,82.7%and87.8%up-to-standard in2011,2012and2013, respectively.(3) Small and medium-scale pig farms (1000≤Number of slaughter pigs/year <3000): The immune antibody of CSF were82.0%,86.7%and85.8%up-to-standard in2011,2012and2013, respectively; the immune antibody of FMD were78.0%,82.7%and84.2%up-to-standard in2011,2012and2013, respectively; the immune antibody of PRRS were74.3%,77.3%and82.5%up-to-standard in2011,2012and2013, respectively.(4) Small-scale pig farms (200≤Number of slaughter pigs/year <1000): The immuneantibody of CSF were75.6%,77.5%and81.8%up-to-standard in2011,2012and2013,respectively; the immune antibody of FMD were73.3%,76.3%and81.8%up-to-standardin2011,2012and2013, respectively; the immune antibody of PRRS were73.3%,77.5%and83.6%up-to-standard in2011,2012and2013, respectively.The results showed that the immune antibody level of CSF, FMD and HP-PRRS indetected farms reach to the70%compulsory standard which required by the state. In thesame year, three kinds of immune antibody levels of vaccinated pigs in big scale farm weresignificantly higher than in small and medium scale farms, indicating that it is important todetect the immune antibody of CSF, HP-PRRS and FMD in farms in this district to preventdisease occurrence.