Effect Of Several Common Feed Additives On Growth Performance,Blood Biochemical Indexes And Economic Benefit In Growing Pigs

This experiment was conducted to evaluate the effects of several common feed additives on growth performance, digestibility, immune function and economic benefit of growing pigs for correctly understanding and using certain feed additive, to reduce feed costs and pig production costs.A total of 80 crossbreed pigs ([Yorkshire× Landrace]× Duroc) at 37.50 ± 1.48 kg of initial body weight was allotted into 5 treatments in 4 replicates with 4 pigs/pen according to randomized completely block (RCB) design feed for 6 weeks. The formulation of control (CON), coated sodium (CSB), coated zinc oxide (CZnO), mixed bacillus subtilis and clostridium butyricum (F10), bacillus subtilis (H10) were meet NRC (1998) recommendation. During whole experiment phase, index of production performance, digestibility, serum biochemical, blood immune and the economic benefit of growing pigs were measured. The results showed that:1)Growth performance:Compared with control group, the group of coated sodium, coated zinc oxide and the mixture of bacillus subtilis and clostridium butyricum were increased by 9.47%,9.34% and 8.71% (P>0.05). Compare to CON the F:G ratio of F10 groups was significantly higher (P<0.05). Between the groups of CSB and F10, H10 and F10 had a significant trend. For the promotion of growth performance, the F10 group is the best.2)Digestibility:The nitrogen intake of F10 were increased by 7.43% and 9.63%,nitrogen retention and digestion were decreased by 5.28% and 13.04% compared to the group of Con and CSB; Compared to the Con the nitrogen retention and digestion of CSB were increased by 10.06% and 2.16%, there was no significant difference between test group and control group (P>0.05)3) Serum biochemistry:There’s a significant difference between the groups of CSB and Con; serum cortisol of F10 was higher than CSB. The BUN of each test groups were all lower than control group,F10 had a significant trend with Con (0.05<P<0.10). The serum glucose levels of CON and F10 were significantly lower than CZnO groups (P<0.05), extremely significantly lower than H10 groups (P<0.01).4) Immune performance:The serum IgG of F10 and H10 groups were obvious higher than CON. also CSB groups (P<0.05). There was no significant difference in serum IgA levels between all the groups (P> 0.05).5) Economic benefit:The feed cost per weight gain of CON and CSB were all extremely higher than F10 (P<0.01), and F10 groups were obvious lower than CZnO groups in the whole growing phase (P<0.05).In conclusion, adding the mixture of bacillus subtilis and clostridium butyricum to the feed formulation of growing pigs can improve the growth performance, increase immune performance, reduce feed and farm production costs to a certain extent.