Effect Of Nourishing Qi To Stop Collapse On Hemodynamics Of Hypodynamic Shock By Using The Pulse Indicator Continuous Cardiac Output Monitor

ObjectiveThe purpose of this study was to observe the effect of shengmai injection which is composed on the basis of nourishing qi to stop collapse in hypodynamic shock patients. Comparing the changes of brain natriuretic peptide(BNP)^shock index (SI) and the hemodynamic parameter through pulse indicates continuous cardiac output (PiCCO) monitor, further discuss its mechanism.Methods24hypodynamic shock patients were randomized into2groups:the comparion group(12patients) and the experiment group(12patients), both of which were given fluid resuscitation and vasoactive agent. The5%glucose injection310ml was dripped intravenous infusion in the comparion group, while shengmai injection60ml was dripped with5%glucose injection250ml in the experiment group. For venous blood collection at the same time, test BNP and SI of two groups. After8hours, observed the changes of patients’cardiac index(CI)、global end diastolic volume(GEDI)、systemic vascular resistance index(SVRI)、 extravascular lung water (EVLW)、mean artery pressure (MAP)、SI and BNP.ResultsBNP was declined in both groups, while of which only the experiment group went down significantly(P<0.05). The CI、GEDI、MAP of both groups rose up to the normal level. It was noticed that the increase detected in the experiment group was higher (P<0.05). SVRI was declined in both groups, while of which only the experiment group went down to the normal level(P<0.05). No obvious change of EVLW was detected between either group(P>0.05).ConclusionsAs the main prescription for nourishing qi to stop collapse, shengmai injection has a beneficial effect on hypodynamic shock by increasing cardiac output and reduction in peripheral vascular resistance, by improves patients’ Hemodynamics.