The Effect Of The Cangling San Formula On The Damp Heat Type Rotavirus Enteritis And Interferon-γ In Infants

ObjectiveThe rotavirus enteritis is a kind of splenasthenie diarrhea. The research team which my teacher joined summarized clinical experience for many years. They consider "damp abundance due to splenic asthenia"is the main pathogenesis in infantile rotavirus enteritis, and had achieved good curative effect with "invigorating spleen for eliminating dampness" for treatment in treating. This method uses the Cangling San formula to treat infantile rotavirus enteritis. Through the observation of clinical efficacy, and the change of content of serum Interferon-γ in before and after treatment. We try to use the theory of serum Interferon-γ to explore the curative effect mechanism of the Cangling San formula to infantile rotavirus enteritis.Methods1. Using simple randomized controlled trials method, the 37 cases who accord with diagnosis standard be divided into two groups, the observation group and the control group. The observation group was given the Cangling San formula, while the control group was given smectite powder. Two groups both were given the essential received alimta and fluid therapy according to the illness. Treatment was 3 days.2. To observe the clinical efficacy, and the change of content of serum Interferon-y in 37 cases before and after treatment.Results1. The content of serum Interferon-y was increase after treatment in the observation group and the control group (P<0.05). Compared to the control, the content of serum Interferon-y in the observation group was more than it (P<0.05)2. The total effective rate was 92%, better than 54% of the control group (P<0.05). Syndrome total score was lower than the control group (P<0.05) after treatment, and there were no adverse reactions.ConclusionThe Cangling San formula has a good effect on infantile rotavirus enteritis. It can significantly improve symptoms, such as stool frequency, abdominal distension and decreased appetite, and the role is safe. The treatment of Cangling San formula to this disease may be to play by improving the content of serum Interferon-y.