Investigate Its Cause Characteristies And Clinical Features

Objective: Fever is a nonspecific symptom in various diseases,prolo- nged febrile itlnesses are diagnostic challenge for the clinician.To diagnosis of fever of unknown origin(FUO) is difficult due to its perplexing causes and multifarious clinical features.Fever is a nonspecific symptom in various diseases,prolonged febrile illnesses are diagnostic challenge for the clinician.To analyze the clinical characteristies of fever of unknown origin(FUO).Between 2013.3--2015.3 patients with FUO were identified by review of patient records of the Department of Fever Related Diseasesin the Second Hospital of Hebei Medical University and their clinical date were analyzed retrospectively.With the analysis of the clinical data, summarize the composition, local FUO case category of disease clinical features, commonly used to assess the diagnosis value, help to clinical diagnosis and treatment period provided for future.Method: Between 2013.3--2015.3 patients with FUO were identified by review of patient records of the Department of Fever Related Diseasesin the Second Hospital of Hebei Medical University and their clinical date were analyzed retrospectively.To explore the difference in distribution of pathogenic cases,review the medial recards retrospecttly summarise and analyze all the 139 pattients with fever admittde to our department between 2013--2015.The diagnosis strategy and etiology distribution characterities of FUO were also discussed,which may be instructive for the diagnosis and treatment of related fever diseases.Results: â‘ Out of the 139 FUO cases,definite diagnosis was eventually achieved in 127 patients(91.37%).The most common causes of FUO were infectious diseases in 85 cases(61.15%).The other causes were vascular connective tssue diseasea in 12 cases(8.63%),tumor and blood system diseases in 5 cases(3.60%),and others in 25 cases(18.00%).However,no definite diagnosis had been made in the remaining 12 casea(8.63%) until they diacharged fron the hospital.â‘¡MAN: infections in 51 cases(36.69%),collagen vascular diseases in 4 cases(2.88%),tumors in 4 cases(2.88%),the other diseases in 14 cases(10.07%),the origin was still unknown in 4 cases(4.32%);FUMAN:infections in 34 cases(24.46%),collagen vascular diseases in 8 cases(5.76%),tumors in 1 cases(0.72%),the other diseases in 11cases(7.91%),the origin was still unknown in 6 cases(4.32%);â‘¢In the group of less than 4 weeksd infections in 40 cases(28.78%),non-infectious in 24 cases(17.27%).In the group of more than 4 weeksd infections in 45 cases(32.37%),non-infectious in 30 cases(21.58%). In the group of less than 4 weeksd and more than 4weeks,infections diseases were slightily higher that of non-infectious diseases.â‘£The final diagnosis method:serum and bacteriological examination in 50 cases(40.00%),diagnostic treament in 43 cases(34.40%),imaging examination in 18 cases(14.14%),tissue biopsy in 14 cases(11.20%).Conclusions: In cause of FUO,infectious diseases wsa the mast common cause.Most of the FUO can be diagnosed by detailed examination and analysis.Infectious diseases,collagen vasular diseases and tumors were still the most common causes of FUO.Careful analysis of clinical data and physical examination results in combination with essentinations are the betterway to detemin the causes of FUO.