| Objective: Through treatment in patients with oral organophosphorus pide poisoning in the process,to observe the influence of the food iesticntake in the recovering of cholinesterase activity in patients and clinical symptoms returned.To clear:The correlation of the feeding time and cholinesterase activity,the clinical symptoms returned,the rebound,complication and the hospitalization days in the patients with oral organophosphorus pesticide poisoning.Methods:1 90 cases of patients with organophosphorus pesticide poisoning were selected in the emergency department in third hospital of xingtai in october 2012 to October 2014. the male 43 cases, 47 cases of women, aged from15 to 82 years old, the average age of 43.26 years. The disease classification With reference to the diagnosis and principles of management of occupational acute organophosphorus pesticide poisoning(GBZ8-2002). Selected patients with conditions as follows: according to the standard of severe poisoning, cholinesterase activity under 30% of the patients with organophosphorus pesticide poisoning.2 The enzyme linked immunosorbent assay was used for determination of serum levels of ACHE.record the patient’s general information: age, gender, previous medical history;All patients except for hepatitis, nephritis, pernicious anemia, malnutrition, myocardial infarction, pregnancy, and so on. Patients were randomly divided into three groups: Group A:Patients with 24~36 hours after poisoning eating;Group B:Patients with 48~60 hours after poisoning eating; Group C:Patients eated after 72 hours in the poisoning. The patients in three groups were treated by adequate gastrolavage and letting patients out and blood purification and absorption of poison,Reuse of compound energy agent and anti-choline detoxification, apply effects antidote.The patients to the hospital detected cholinesterase activity level, renal function, electrolyte, live r function test indexes and observe the changes of clinical symptoms of recovery,have occurred the rebound, intermediate syndrome, toxicity of neuropathyevery day.By comparing test indexes of recovery of the cholinesterase activity level in1,3,5,7days, To explore the correlation between the eating time and the recovery of the cholinesterase activity and the rebound and the hospitalization days in patients with the oral organophosphorus pide poisoning.3 measurement data with X-±s,the age by using single factor analysis of variance, gender was using χ2 test, hospitalization days and the eating time relationship by using single factor analysis of variance, cholinesterase activity relationship with the time of food intake by variance analysis of repeated measurement data, Complications were chi square test.Using SPSS 16.0 software processing data, in order to P<0.05 representatives had statistical significance.Results:1 The was relationship with the time of food intake and cholinesterase activity recovery : the sooner the meal time, the shorter the cholinesterase activity recovery time(F=1023.328,P=0.001,P<0.05).2 There was a correlation between with eating time and hospitalization days in patients,the ealyer the patients intake food, the later the hospitalized days.(F=4.439,P=0.015,P<0.05).3 The three groups in the middle of the treatment are not occurred in the observation syndrome, late-onset neuropathy and bounce,The incidence of complications was not statistically different.( p=0.993, P>0.05).Conclusion:1 There was a relationship with the time of food intake and the cholinesterase activity in patients with organophosphorus pesticide poisoning, the sooner the meal time, the faster cholinesterase activity recovery.2 There was no correlation between the time of food intake and rebound in the patients with oral phosphorus pesticide poisoning patients, early to eat done not increase the incidence of patients bounce.3 There was a correlation between feeding time and hospitalization days in the organic phosphorus pesticide poisoning patients, early eating can shorten the hospitalization days. |
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