Prepatation And Evaluation Ofyinluo Capsule

In this paper, the treatment of cerebrovascular disease is one of the most common inischemic stroke disease of traditional Chinese medicine compound preparations made asystematic research on the silver complex capsules. Research contents include:1. Thepreparation of the research;2. Quality standard research;3. Study the stability of thepreparation. Preparation technology study, rhubarb shatter into meal, with ginkgo leaf and50%ethanol reflux extraction twice, the first time+14times,+10times a second time,extracting2hours at a time, merge extract, filtration, the filtrate recycling ethanol,condensed into a relative density of1.35~1.38(55℃) clear cream; Rhizoma ligusticiwallichii, basil essential oil, rhizoma ligustici wallichii smash into coarse powder, and basilwith eight times the amount of water, immerse2hours, steam distillation extraction ofvolatile oil,5hours to collect volatile oil, the distillation of aqueous solution of another;After the extraction of volatile oil of liquid to add10times the amount of water decoctiontime, decoction for2hours, decoction liquid filtration, the filtrate after the essential oilswere extracted with aqueous solution of merger, enriching to relative density is1.05~1.08(55℃), and ethanol alcohol content is50%, stir and let stand for eight hours, filtration, thefiltrate recycling ethanol, condensed into a relative density of1.35~1.38(55℃) of the paste. Will clear cream merger of the extract, mixing, drying, crushing, take five timesthe amount of volatile oil beta cricoid dextrin, add2times the amount of20%ethanol,ground into a paste, to join the volatile oil, grinding for2hours, low temperature drying,crushing, add the extract powder and the right amount of starch, add3.5g magnesiumstearate, blending, encapsule, made1000grains, quick; Quality standards using TLCmethod for preparation of rhizoma ligustici wallichii, basil, rhubarb specificity identification,by the method of HPLC, the content of total flavonoids from ginkgo biloba leaves glycolglycosides in preparations was determined. Examine the initial stability of the preparation,according to the preliminary stability of observation of three batch samples, the resultsshow that silver collaterals capsule under the condition of the plastic bottle packagingquality stability is good.