The Obdervation Of Adverse Reactions Of The Digestive Tract In Patients With Gastrointestinal Cancer Receiving Chemotherapy With Depression And Anxiety Mood

Objective:To assess the prevalence of anxiety and depression in chemotherapy for gastrointestinal cancer patients, and to explore the presence of gastrointestinal reactions and investigate their relationships with anxiety and depression.Methods:One week after chemotherapy treatment,74gastrointestinal cancer patients were evaluated by self-rating depression scale (SDS), self-rating anxietyscale(SAS) and WHO test preparation "Common side effects of anticancer drugs Questionnaire".Results:The incidence rate of anxiety of acute advanced gastrointestinal cancer patients treated with chemotherapy was21.62%, the incidence rate of depression was31.08%. Anxiety and depression were positively correlated (r=0.726, P<0.05). Anxiety and depression were positively correlated (r=0.726, P<0.05). There was no significant correlation among SAS scores and gender, age, stage (P>0.05). There was also no significant correlation among SDS scores and gender, age, stage (P>0.05). Both in highly emetogenic and non-highly emetogenic group we found that nausea and vomiting, oral mucositis and anxiety correlated (P<0.05). We also found in highly emetogenic group oral mucositis correlated with depression (P<0.05).Conclusions:Patients with advanced gastrointestinal cancers have a higher incidence of depression and anxiety. There are relationship between anxiety and gastrointestinal symptoms of nausea and vomiting in gastrointestinal patients receiving chemotherapy.