Research On Lungs Governing Dispersing And Descending And Therapeutic Principles Of Wheezing Disease Based On Ancient Medical Cases In Chinese Medical Classic

Objectives: Based on the study of disease causes, symptoms, therapeutic principles and methods and prescriptions and formula of wheezing disease, the paper probes into the relations between lung failing to disperse and descend and patterns of wheezing disease.Methods: Theoretical analysis and case study are adopted in the research. 1. Theoretical study: Combined with TCM classics such as Canon of Medicine and Treatise on Cold Damage Diseases and some relative research materials, the paper discusses the relations between the theory of lungs governing dispersing and descending and the etiology and pathogenesis of wheezing disease. 2. Case study: By selecting the relative case records in Chinese Medical Classic, the paper analyzes 173 wheezing disease cases under the assistance of TCM inheritance software.Results:1. Theoretical study shows that there is close relationship between lung governing dispersing and descending and the onset of wheezing disease, with lung failing to disperse and descend being the pathogenesis of wheezing disease, and dispersing and descending lung qi being the main therapeutic method. 2. Case study indicates the following findings.(1) In terms of pathogenic factors, there are 44 cases of cold pathogen being the cause of wheezing disease, accounting for 24.9%; 25 cases of phlegm and retention being the cause, accounting for 14.1%; 25 cases of congenital weakness being the cause, accounting for 14.1%; 19 cases of wind pathogen being the cause, accounting for 10.7%.(2) In terms of location of disease, there are 100 cases of locations being in the lungs, accounting for 57.8%; 16 cases being in the lungs and spleen, accounting for 9.2%; 16 cases being in the lungs, spleen and kidneys, accounting for 9.2%; 12 cases being in the lungs and spleen, accounting for 6.9%. Among all the cases, 95.9% of the cases are directly related the spleen.(3) In terms of therapeutic methods, there are 40 cases adopting clearing method, accounting for 23.1%; 25 cases adopting warming method, accounting for 15%; 23 cases adopting tonifying method, accounting for 13.3%; 19 cases adopting sweating method, accounting for 11%; 16 cases adopting resolving method, accounting for 9.2%.(4) Under the assistance of TCM inheritance software, we get the frequency of wheezing disease in terms of symptoms: 148 times for wheezing, 124 times for asthmatic breathing, 75 times for coughing phlegm. The frequency of medication includes 84 times for poria, 83 times for bitter apricot seed, 72 times for pinellia tuber and 55 times for perilla seed. The main syndromes of wheezing disease include pattern of phlegm-heat obstructing lung(42 cases), turbid phlegm obstructing lung(32 cases), cold phlegm obstructing lung(18 cases) and exterior cold with interior fluid retention(12 cases).(5) In terms of the relations between lungs failing to disperse and descend and patterns of wheezing disease, there are 116 cases belonging to the pattern of lungs failing to descend. Among them, 43 cases belong to pattern of phlegm-heat obstructing lung, 33 cases to turbid phlegm obstructing lung, 18 cases to cold phlegm obstructing lung, 10 cases to deficiency of both lungs and kidneys, 5 cases to phlegm-heat obstructing lung combined with deficiency of both lungs and kidneys, and 7 cases to other patterns. There are 34 cases belonging to the pattern of lungs failing to disperse. Among them, 12 cases belong to the pattern of exterior cold with interior fluid retention, 7 cases to cold-retention affecting the lungs, 7 cases to wind-phlegm affecting the lungs, 5 cases to exterior cold and interior heat, 3 cases to wind-cold fettering lungs. There are 10 cases belonging to the pattern of lungs failing to disperse and descend. Among them, 8 cases belong to spleen-lung qi deficiency pattern, one for spleen-lung qi deficiency combined with food accumulation, and still another one for phlegm-heat obstructing lungs combined with spleen-lung qi deficiency. And what’s more, there are still 13 cases belonging to other patterns.Conclusions:Cold pathogen is the major exogenous factors causing wheezing disease, which is followed by phlegm retention, congenital weakness and wind pathogen in turn. The major location of wheezing disease is the lung, which is also closely related to the spleen and kidneys. Clearing method is the major therapeutic method to treat wheezing disease, which is followed by warming, tonifying, sweating and resolving methods in turn. The common symptoms of wheezing disease include wheezing, asthmatic breathing, phlegm and cough. The common herbs for wheezing disease include poria, bitter apricot seed, pinellia tuber and perilla seed. The main syndromes of wheezing disease include pattern of phlegm-heat obstructing lung, turbid phlegm obstructing lung, cold phlegm obstructing lung and exterior cold with interior fluid retention. The pathogenesis of wheezing disease is lung failing to disperse and descend, failing to descend being in particular. The major therapeutic method for wheezing disease is to disperse and descend lung-qi, which is especially true of restoring the lungs’ function of descending.