The Clinical Observation Of Ju Yuanjian In Preventing And Treating Hypotension Of Hemodialysis Patients

The purpose:Clinical research of this study is to give Ju Yuan Jian by using prevention maintenance hemodialysis patients hypotension observed medical treatment dialysis hypotension efficacy and safety, and explore effective treatment of hypotension in hemodialysis patients.Method:1. Select at Garden Hill Hospital of Hubei Province Optical Valley School District School District and the hemodialysis unit for treatment of 27 patients, 27 patients met the inclusion criteria hemodialysis refractory hypotension, hypotension during hemodialysis in greater than 80% probability. The patients were randomly divided into two groups, the treatment group(for Ju Yuan Jian group) 14 cases and the control group of 13 patients in the control group were given basic treatment in general, to be the usual manner only when hypotension during dialysis, the treatment group were based on the addition of flavored give Ju yuan Jian(ginseng, Atractylodes, Cimicifuga, astragalus, licorice, citrus aurantium, Epimedium, salvia, Yiyiren) treatment. Treatment time is two months to observe its efficacy and safety.2. Outcome Measures measurement of blood pressure, the dialysis process measurement of blood pressure at intervals of one hour, the patient record once a week KT / V values before and after treatment to check renal function and blood, the symptoms observed in patients with hypotension and to a time before and after dialysis before treatment and after treatment for patients with syndromes line questionnaire.3. Statistical Processing applications SSPS17.0 software for statistical analysis, count data using X2 test, measurement data using t test, with Ridit level data analysis, P <0.05 considered statistically significant.The results:1.The total effect of comparison: the treatment group was higher than efficiency, there was a significant difference between the two groups, indicating that the Ju Yuan Jian has a good effect on the dialysis hypotension2. The incidence of hypotension comparison: the treatment group in January, hypotension occurred after February were lower than the control group, with significant differences, indicating that Ju Yuan Jian can effectively reduce the incidence of dialysis hypotension.3. Patient tolerance compared to dialysis hypotension: In all cases occur after dialysis hypotension, the treatment, mainly for asymptomatic hypotension, there was a significant difference compared with the control group, suggesting that dialysis can reduce Ju Yuan Jian symptoms of hypotension occurs, increase tolerance to dialysis hypotension.4. Hypotension during dialysis start time comparison: during dialysis treatment, after the start time has been delayed hypotension, compare with the control group, a significant difference, indicating that the Ju Yuan Jian can delay the start of dialysis hypotension occurred.5. Compare KT / V values: KT / V value in the treatment group than the control group, with significant differences, indicating that Ju Yuan Jian can help improve dialysis adequacy. ysis.6. Comparison of biochemical indices of the two groups of patients before and after treatment: After treatment Scr, P values decrease, Bun, Hb value increased, and the control group were significantly different.7. Total score of TCM symptoms before and after treatment comparison: After treatment, the TCM symptom scores were lower than the control group, with significant differences, indicating that Ju Yuan Jian can effectively improve the clinical symptoms of dialysis patients. 8. Syndromes total effect of comparison: After treatment, the total effect was higher syndromes, there are significant differences, also showed Ju Yuan Jian dialysis patients can improve clinical symptoms.9. Security Analysis: During the treatment group treatment observation, electrocardiogram, liver function and other laboratory examinations and biochemical parameters did not appear obviously abnormal, the patient’s condition is stable, no significant difference compared with the control group, no obvious adverse reactions occur, the security problem does not occur. In conclusion:Ju Yuan Jian can effectively reduce the incidence of hypotension in hemodialysis patients and reduce symptoms in patients with dialysis hypotension occurs, increase patient tolerance to dialysis hypotension, dialysis hypotension delay time and improve dialysis adequacy reduce serum creatinine and serum phosphorus levels, increased hemoglobin levels in patients, reducing the clinical symptoms.