Kidney Invigorate The Circulation Of Particles Of Senile Hypertension Patients The Effect Of Vascular Endothelial Function And Arterial Elasticity

Objective: this study by collecting clinical case analysis and research, to observe kidney invigorate the circulation of particles endothelial function of elderly hypertensive patients and the clinical curative effect of arterial elasticity. By comparing elderly hypertensive patients before and after treatment of traditional Chinese medicine clinical symptom scores, random blood pressure, serum levels of endothelin 1(ET 1), nitric oxide(NO) and carotid intima-media thickness(IMT), pulse wave velocity(PWV) and ankle-arm index(ABI), and other indicators of change, analyzing the mechanism of kidney invigorate the circulation of particles and the value in clinical application.Methods: under the condition of maintain routine western medicine to lower blood pressure, will be the clinical diagnosis of 120 cases of senile hypertension and conform to the kidney and blood stasis type of traditional Chinese medicine diagnosis of the patients were randomly divided into two groups, control group 60 cases, high blood pressure level 1 give nifedipine zyban; High blood pressure level 2 give nifedipine zyban, valsartan capsules of conventional western medicine treatment; Experimental group 60 cases, while maintaining the same as the control group of western medicine treatment of kidney invigorate the circulation of particles was given on the basis of one time in the early to middle, two experiments of treatment for 12 weeks, respectively in 2 weeks, 4 weeks, 6 weeks, 8 weeks and 10 weeks, 12 weeks after testing related experimental indexes, and analyze the curative effect.Results: the clinical observation, after 12 weeks of drug intervention, the experimental group in reducing the elderly hypertension obviously better than that in control group(P < 0.05), the clinical symptoms of senile hypertension patients have obvious improvement, visible at the same time serum endothelin 1(ET 1), nitric oxide(NO) and carotid intima-media thickness(IMT), pulse wave velocity(PWV) and ankle- changes in arm index(ABI) indicators were significantly lower. Two groups of elderly hypertensive patients in the trials for various safety indexes before and after treatment not seen anomaly.Conclusion: observation of the clinical experiment research indicated: kidney invigorate the circulation of particles in the treatment of senile hypertension belongs to the kidney and blood stasis type of patients has good clinical practical curative effect, can very good control of blood pressure, improved the patient’s clinical symptoms, and serum levels of endothelin 1(ET 1), nitric oxide(NO) and carotid intima-media thickness(IMT), pulse wave velocity(PWV) and ankle- arm index(ABI) the change of the index have a certain degree of reducing effect. Kidney invigorate the circulation of particles can improve endothelial damage, delay the development of atherosclerosis, effective prevention and treatment of cardiovascular events.