| Objectives Investigate the pathogenesis of thyroid cancer risk factors, providing theoretical basis for early prevention of thyroid carcinoma. Analyze the ultrasonic characteristics of thyroid cancer to provide theoretical basis for the early diagnosis of thyroid carcinoma.Methods 1 The investigation of risk factors of thyroid cancer. Collected 180 cases in the Tangshan Gongren hospital, Tangshan people’s hospital, Hebei united university affiliated hospital and Tangshan TCM hospital, from October, 2013 to October, 2014.These cases are all had the surgery and the postoperative pathology is thyroid cancer.With the method of case-control study, selected 180 healthy people in these hospitals as control group in the same period. Matching conditions: the same gender, age difference 3years. Questionnaire survey was conducted in two groups, the content of the questionnaire includes: diet and living habits, family history of cancer, medical history,family history of thyroid illness, mental stress, history of smoking, drinking, etc.Combining with body mass index, blood glucose, blood lipid, thyroid function, etc.Information obtained will be input to a database of Excel table, using SPSS17.0 statistical software for data analysis, single factor analysis using chi-square test, single factor analysis are statistically significant factors of unconditioned Logistic regression analysis.2 The research of ultrasonic diagnosis of thyroid cancer. Collected 180 cases of thyroid cancer in patients from October, 2013 to October, 2014 in the same hospitals for surgical treatment, a total of 293 nodes and 180 patients with benign nodules, a total of 323 nodes. Collect preoperative thyroid ultrasound results, including: the number of nodules,internal echo, the boundary, shape, aspect ratio, flow conditions, etc, using SPSS17.0statistical software analysis the ultrasonic signs, use chi-square test count data mining,analysis of ultrasonic features of thyroid carcinoma.Results 1 The survey of risk factors of thyroid cancer. 131 cases of 180 cases of thyroid cancer in patients are women, accounting for 72.8%. Men have 49 cases, accounting for27.2%. The sex ratio was 1:2.67, the female incidence ratio was higher than men. Single factor analyzed in the case group and control group showed that staying up late, eating seafood frequency, body mass index, stress, bad mood, anxiety, blood glucose, increasedthyroid autoantibodies, thyroid disease history, family history of thyroid disease, tumor family history are thyroid cancer risk factors, have significant difference in two groups(P<0.05). Factor of single factor analysis statistically difference between binary Logistic regression analysis showed that eating seafood frequency, body mass index, bad mood,elevated blood sugar, anxiety, staying up late in multi-factor analysis with statistical significance. 2 Analysis of characteristics of ultrasound of thyroid carcinoma.180 cases of thyroid cancer, a total of 293 nodules, compared with 180 cases of benign lesions, a total of 323 nodes, found that the incidence of thyroid cancer has nothing to do with the single and multiple nodules, thyroid cancer characterized by low echo more solid nodules,boundary owes, shape owe neat, internal tiny calcification, aspect ratio 1, rear attenuation,nodules or internal and peripheral has the rich blood flow signal, and benign nodules compared with significant difference(P<0.05).Conclusions 1 The incidence of thyroid cancer of women is higher than men. 2 Single factor analysis shows that staying up late, eating seafood frequency, body mass index,stress, bad mood, anxiety, blood glucose, increased thyroid autoantibodies, thyroid disease history, family history of thyroid disease, family history of cancer are risk factors for thyroid cancer. 3 Multiple factors analysis shows that eating seafood frequency, body mass index, bad mood, elevated blood sugar, anxiety, staying up late having statistically difference between the two groups. 4 Benign and malignant thyroid nodules has nothing to do with the single and multiple nodules. 5 Thyroid cancer is largely confined to low echo solid nodules, boundary owes, shape owe neat, tiny calcification, aspect ratio 1, rear echo attenuation, nodules or internal and peripheral having the rich blood flow signal,prompt significance to the diagnosis of thyroid carcinoma. |