The Analysis Of Magnetic Resonance Imaging After Intratympanic Gadolinium Injection For Patients Of Idiopathic Sudden Sensorineural Hearing Loss.

Objectives: We used three-dimensional fluid-attenuated inversionrecovery magnetic resonance imaging(3D-FLAIR MRI) to investigateendolymphatic hydrops(EH) in patients of Idiopathic Sudden SensorineuralHearing Loss(ISNHL) with and without vertigo.Methods: Forty-five patients with unilateral ISNHL were classifiedinto ISNHL with vertigo group and ISNHL without vertigo group. Allpatients were recorded medical history, pure tone audiometry and 3D-FLAIRMRI after intratympanic injection of gadolinium–diethylenetriaminepentaacetic acid.Results: Among the 45 patients of ISNHL, 22.6%(7/31)had EH in vertigogroup, 35.7%(5/14) had EH in ISNHL without vertigo group. The locationof EH was noted in the cochlea in 28.6%(2/ 7) patients of EH with vertigo,and 80%(4 / 5) patients of EH without vertigo had EH in the cochlea. Thelocation of EH was noted in the vestibule in 100%(7/ 7) patients of EHwith vertigo, and 40%(2 / 5) patients of EH without vertigo had EH inthe vestibule.Conclusions: There was no significant difference in the general ratesof EH in those patients with vertigo and those patients without vertigo.EH occurred more frequently in vestibule in patients of EH with vertigogroup than EH without vertigo group.