Influences Of Different Coagulation Methods On Ovarian Function During Laparoscopic Ovarian Mature Teratoma Cystectomy

Objective With the development of the society and the advance of medical technology,people for the technical level of the disease treatment and the personal mental state and quality of life requirements after treatment also increased a lot. Laparoscopic surgery has become the preferred method to treat ovarian teratoma, but for mature ovarian teratoma and ovarian function as well as laparoscopic mature teratoma removed after different hemostasis method the impact on ovarian function, There is also no precise indicators,nor to draw definitive conclusions at present.This paper compared mature ovarian teratoma ovarian function in patients with healthy groups,the mature teratoma patients undergoing surgery were divided into coagulation and suture hemostasis group.Study changes in their ovarian function and seek out more sensitive evaluation,explore whether mature ovarian teratoma has an effect on ovary reserve function, and find the better stop bleeding way to protect the ovarian function.Methods Selected normal women of childbearing age(control group) 40 cases a nd laparoscopic ovarian teratoma excision of 40 cases of patients(Study Group) in Beijing Military Region General Hospital Department of gynecology and obste trics examination from February 2014 to 2015 July. The study group of 40 patie nts were randomly divided into two groups: used suture hemostasis method calle d suture group(20 cases) and bipolar coagulation hemostasis method calle electr ocoagulation group(20 cases). Study group before surgery last month menstruatio n, 3 days and 1,3, 6 months after surgery, patients in the control group before surgery last month in second to four day of menstruation 8:00- 9:00 drawn 3- 5ml venous blood to check estradiol,follicle-stimulating hormone,luteinizing hormo ne,anti-mullerian hormone.Comparison of preoperative study group and the control group of ovarian function, postoperative ovarian function in different hemostasis methods.To evaluate the influence of different hemostatic method for ovarian res erve function.Results(1) Compared study group with the healthy control group the general situation, two groups of age, BMI, LH, E2,FSH the difference was not statistically significant(P> 0.05).However, the Study Group AMH level is lower than the healthy control group, the differences were statistically significant(P <0.05).Electrocoagulation group and suture group the serum paprameters LH, FSH, E2 change between groups for each postoperative time period, difference was no significant difference(P> 0.05). But the level of AMH at postoperative different time between the two groups was statistically significant(P <0.05).(2) Coagulation group after three days of surgery ovarian function LH value increased beyond the normal range, a gradual decline followed to 6 months to normal levels. Suture group every time after surgery were compared with the preoperative period,the difference was not statistically significant(P> 0.05).Postoperative time points compared with the preoperative value FSH, in both groups after three days of surgery ovarian function FSH indexes were significantly increased,after operation in March began decreasing to normal levels, but still more high than the preoperative,differences were statistically significant(P <0.05).Postoperative time points compared with the preoperative value E2, the difference was not statistically significant(P> 0.05).AMH fell both in two group 3 days after surgery,and then gradually restored,until 6 months the AMH levels restored to preoperative in coagulation group.Suture group gradually recoveried postoperative 1 month to the preoperative level, 6 months after surgery the ovarian function AMH was better than before surgery, the differences were statistically significant(P <0.05). After the two groups at each time point ovarian function declined number ratio was no significant difference, the difference was not statistically significant(P> 0.05).Conclusion(1) To better evaluation of ovarian function, Measurement Indicators AMH is better than FSH, LH, E2.(2) Mature teratoma patients with low serum AMH than healthy women,it may affect ovarian function, the clinical situation should be noted that mature teratoma patients’ ovarian function.(3) Suture hemostasis is more conducive to protecting ovarian function compare with electrocoagulation hemostasis in laparoscopic mature teratoma removed operation,These findings may guide clinical diagnosis and treatment operations in mature teratoma, mature teratoma stripping surgery using hemostasis clinical methods worthy of further promotion.