| ObjectiveIn terms of haemodynamics characteristics of ischemic stroke with Qi deficiency and blood stasis in Chinese traditional and western medicine, the cerebral arerio-venous pulse wave time (CAV-PWT)of ischemmic stroke patients with Qi deficiency and blood stasis is studied and the relevance of CAV-PWT of these ischemic stroke patients,relative indicators in haemodynamics and carotid artery condition is analyzed and discussed, which provide new basis for prevention, diagnosis and treatment of ischemic stroke patients with Qi deficiency and blood stasis.Methods22 cases of hospitalized patients dying of lacunar infarction with Qi deficiency and blood stasis during the period from October 2014 to May 2015 are selected from Shenzhen Secondary People’s Hospital. The average age is (67.36±12.82) years old and 11 male cases and 11 female cases are taken;20 cases of atherosclerosis cerebral infarction patients with Qi deficiency and blood stasis are taken and the average age is (63.4±11.98) years old. 13 male cases and 7 female cases are taken.20 cases of people taking part in physical examination and simultaneously going to the same hospital are taken as the control group. The average age is (58.17±13.02) years old, including 12 male cases and 8 female cases. Transcranial doppleul transonograp (TCD) is used to synchronously monitor the pulse wave of terminal internal carotid artery (TICA) and Rosenthal’s veins (venae basalis, BVR) and calculate CAV-PWT. SPSS 19 is used to make statistic analysis for the obtained data and the single factor analysis method is sued to compare relative variable differences.t is used to inspect the comparison between two groups means and chi-square test is performed for enumeration data. Pearson analysis method is used to make relative analysis for variables conforming to normal distribution and logistic regression analysis of relevance of multivariables. Inspection level α=0.05.Results1. There are statistics differences in LI group with Qi deficiency and blood stasis, LAA group with Qi deficiency and blood stasis and control group after comparison (p<0.05) and is no statistics significance in comparison difference in LI group with Qi deficiency and blood stasis, LAA group with Qi deficiency and blood stasis. (p>0.05)2. Negative relevance exists in CAV-PWT,age and HCY (r=-0.425,-0.29, P＜0.05); no relevance in height, weight, weight index, head circumference, FBG,2h-PBG,TG,CHO,LDL-C and HDL-C(P>0.05).3. Negative relevance exists in CAV-PWT,heart rate, systolic pressure, diastolic pressure, pulse pressure and mean arterial pressure (r=-0.048,r=-0.039,r=-0.29,r=-0.33, r=-0.25,P＜0.05)4. Outstanding positive relevance exists in CAV-PWT (r=0.42, P＜0.01) and LVEF, which is irrelevant with LVS and LVD (P>0.05).5. Relevance exists in L-CAV-PWT, LTICA-PI,LTICA-RI,LBVR-PI and LBVR-RI (r=-0.28, r=-0.26, r=0.27, r=0.27, P＜0.05) and this condition also appears in the right side and is irrelevant with Vs and Vd.6. Outstanding negative relevance (L-r=-0.55, R-r=-0.59, P＜0.05) exists in CAV-PWT and carotid plaque length, which is irrelevant with plaque thickness (P>0.05). Outstanding positive relevance exits in CAV-PWT carotid atherosclerosis (L-r=0.00, R-r=0.00, P＜0.01).Conclusion1. Ischemic stroke patients with Qi deficiency and blood stasis have cerebral arteriosclerosis of different degrees;2.Ischemic stroke patients with Qi deficiency and blood stasis are closely related to CAV-PWT, heart rate and LVEF., which means heat Qi deficiency plays an important role in the change of heart haemodynamics of ischemic stroke.3. CAV-PWT of ischemic stroke patients with Qi deficiency and blood stasis is related to PI and RI and is irrelevant with blood flow velocity, which means CAV-PWT mainly reflects indicators of vessel wall compliance and blood vessel resistance,but blood flow velocity has little influence on blood flow velocity.4. CAV-PWT of ischemic stroke patients with Qi deficiency and blood stasis is closely related to carotid plaque length and is irrelevant with plaque thickness. It means that in case the existence of plaque apparently influences the diameter of the blood vessel and has little influence on CAV-PWT. But the length of the plaque has great influence on CAV-PWT,because the distance of artery stiffness segment is directly affected. |
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