The Clinical Efficacy Of The Method Of Smoothing Liver And Adjusting Stomach In The Treatment Of Bile Reflux Gastritis With Liver Stomach Disharmony Type

Objective:To observe the clinical efficacy of the method of smoothing liver and adjusting stomach in the treatment of BRG with liver stomach disharmony type.Methods:44 patients with liver-stomach disharmony BRG were selected. The subjects were randomly divided into treatment group and control group,22 cases each group. The patient’s gender, age, disease course, illness state as well as gastroscopic bile regurgitation degree and TCM syndrome score before surgery was not significantly different (P>0.05). The therapy of smoothing liver and adjusting stomach was taken for one dose a day, two times in the morning and evening. The control group took 5mg of mosapride tablets for 3 times a day (before 30min of meal); the control group orally took 20mg of omeprazole capsule in the morning and evening. Two treatment courses were taken,4 weeks a course. The clinical symptom and signs were recorded; after treatment, the total effective rate, TCM symptom and TCM syndrome score was compared. Through SPSS 17.0, the measurement data was expressed by (x ±s) "mean+standard deviation". The test of normality and homogeneity of variance was conducted. In view of normality distribution and no significant differences, the t test was avaliable; in view of abnormal distribution and significant differences, the non-parameter test (rank-sum test) was conducted. Based on the targeted cases, x2 and rank-sum test was conducted (P<0.05).Results:After treatment, the total effective rate of treatment group (86.36%) was significantly higher than that of control group (77.27%) (P<0.05); the score of TCM syndrome for treatment group was better than that of control group (P< 0.05);the symtom (except for bitter taste) for treatment group was improved; for control group, the symptoms of heartburn, sighing, lose of appetite, depression were not improved.Conclusions:The method of smoothing liver and adjusting stomach has an obvious effect in the treatment of liver-stomach disharmony BRG, has higher safety, has no obvious adverse reactions, improves the patient’s life quality.