Chinese Drugs Of Chongqing Coptis Processing Key Technology And Quality Standards

Rhizoma coptidis is from the roots of coptidis plants huanglian, Triangle coptis, Yunnan coptis. It taste bitter and cold, it can into the heart, stomach, liver, colon, it used to be detoxification, dryness, purging fire of commonly. Modern pharmacological studies showed that rhizoma coptidis have antimicrobial, antiviral, anti-inflammatory activity, immune regulation, lower blood sugar, more targets the AD effects, regulating the cardiovascular system, antitumor activity, inhibiting topoisomeraseⅡ,anti-arrhythmic, analgesia, sedation, and malaria.In this paper, the varieties of wine rhizoma coptidis rhizoma coptidis specified on the orthogonal test, by analyzing the content of total alkaloid determination to find the best processing technology. As a case study of rhizoma coptidis wine processing, the key technology to control points for the detailed research. Exploratory work out a set of wine rhizoma coptidis production processing technical process.By HPLC to analysis the main alkaloids in Coptis such as jatrorrhizine, Coptisine, berberine table, Palmatine and berberine.So, through orthogonal test choose the best processing technology of wine rhizoma coptidis total alkaloid content. Can clear the source, origin, collecting time, forming processing technology, build process comprehensive quality control system in Chinese medicine, Chinese medicine processing specification and explore the useful experience for the establishment of quality standard.