Study On Chemical Constituents Of Xanthium Mongolicum

Xanthium mongolicum Kitag is belong to Xanthium L.Genus, Compositae family. The distribution was reprted in dongbei, Inner Monglia and Hebei.It has the effect of antiviral, antioxidant, anti-inflammatory analgesic and so on. Xanthium mongolicum is used in treating rhinorrhea, wind-cold, skin eczema, leprosy and itch, whitch is a kind of important wild medicinal plants.In our investigation, The Xanthium mongolicum were extracted with anhydrous alcohol, after filtration and concentrate. Preparationextract of Xanthium mongolicum were extracted with n-Hexane, ethylacetate and n-Butanol, respectively. Thirty compounds were isolated by silica gel column chromatography and HPLC from n-hexane, ethylacetate and n-Butanol fraction extract from the Xanthium mongolicum, The chemical structures of the constituents were identified by means of physic-chemical and spectral date, They are: Olein(1), Glycerol linoleate(2), ?-sitosterol(3), lasidiol p-methoxybenzoate(4), stigmasterol(5),?-selinene(6), xanthatin(7), xanthinosin(8), Luteone(9), ?-apinasterol(10), 4?,5?-epoxyxanthatin-1?,4?-endoperoxide(11), Glyceol trioleate(12), vomifoliol(13), dehydrovomifoliol(14), Linoleic acid(15), 4-oxo-bedfordia acid(16), 11?,13-Dibydra-8-epi-xanfbut(17),(3R,6R,7E)-3-Hydroxy-4,7-megastigmadien-9-one(18),scopoletin(19), pinoresinol(20), quercetin(21), methyl p-hydroxybenzonate(22), Tetracosane(23), Daucostero l(24), Z-3-hexenyl-?-D-glycoside(25), saccharose(26). Among them, compounds 4, 6, 9, 11, 13, 14, 16, 19, 22, 25 were isolated from this plant for the first time.