| Objective:This topic through ankle fracture etiology and pathogenesis,diagnosis, complications recognized, compared Huoxue Zhongtong Decoction group ? seven sodium aescinate group and Huoxue Zhongtong Decoction+ seven sodium aescinate group to treat ankle fracture and observed the clinical efficacy of swelling and pain. After analyzing and evaluating the use of ankle fractures early clinical significance of Huoxue Zhongtong Decoction, to further promote its use in clinical practice to provide evidence.Methods:This topic research into the cases were patients from February2015 to December 2015 at the First Affiliated Hospital of Anhui Medical University during orthopedics hospital patients, choose a standard total of60 cases.Among them, the men 38 cases, 22 cases of female, age range from18 to 64 years old, average(38.77 ± 3.86).Randomly divided into three groups, each group 20 cases, respectively,for Huoxue Zhongtong Decoction group(hereinafter referred to as Chinese medicine), seven sodium aescinate group and Huoxue Zhongtong Decoction+seven sodium aescinate group(hereinafter referred to as combination group).Three groups have to be the same normal processing, at the same time, the Medicines for oral Huoxue Zhongtong Decoction began to give way on the first day after admission,one dose a day, the day of surgery to disabled.The combination group began to be oral Huoxue Zhongtong Decoction on the first day after admission and intravenous infusion of seven sodium aescinate, medication and dose with the former method, the day of surgery to disabled.Respectively to observe and record the three groups before treatment, the 3th day, 5th day and the7 th day of the ankle joint and soft tissue swelling score, swelling, pain(VAS score), wait time, preoperative limb deep venous thrombosis cases,perioperative complications of cases and the change of liver and kidney function main indicators before and after the treatment.All the clinical data of 60 cases of subject by use of statistical software SPSS 19.0 for data processing, analysis and comparison of three groups of observation indexes and evaluate the clinical efficacy of three groups.Results : 1 This topic into three groups of subjects before treatment in gender, age, cause, fracture position, degree of limb swelling in the ankle,and other general information obtained with statistical analysis were no statistical difference(P>0.05), showed comparable between three groups.2 Ankle joint soft tissue swelling integral aspects: three groups before treatment to compare differences had no statistical significance(P>0.05);Combination therapy 3 days group, the difference compared with before treatment(P<0.05), but the other two groups there was no statistically significant difference(P>0.05); Three groups of treatment for five days, 7days clear difference compared with before treatment(P<0.05, P<0.01), the three groups were separately SNK- q test, two comparative differences are statistically significant(P<0.05, P<0.01). Which reduce the size of the combination group was obviously superior to the single drug group, the most significant curative effect, Chinese medicine group took the second.3 Ankle joint soft tissue swelling degree: three groups before treatment to compare differences had no statistical significance(P>0.05); Combination therapy 3 days, Medicine group the difference compared with before treatment(P< 0.05), but aescinate sodium group differences had no statistical significance(P> 0.05); Three groups of treatment for five days, 7days clear difference compared with before treatment(P<0.05, P<0.01), the three groups were separately SNK- q test, both two more significant differences(P<0.05, P<0.01). The combination group of swelling speed more quickly, work faster, curative effect is significantly better than the single drug group; Chinese medicine group with the increase of treatment time, swelling effect is superior to aescinate sodium group.4 Ankle swelling effect aspects: treatment for 3 days, three groups of clinical curative effect of detumescence, there was no statistically significant difference(P> 0.05); Three groups of five days, 7 days before and after treatment clinical curative effect of detumescence is significant difference(P<0.05, P<0.01), Chinese medicine treatment of 7 days group compared with aescinate sodium group difference was statistically significant(P<0.05). The combination group in the treatment of 5, 7 days to reach optimum, a good number of the subjects obviously higher than that of single treatment group, the most significant clinical effect of detumescence,Chinese medicine group took the second.5 Ankle pain VAS score: three groups before treatment to compare differences had no statistical significance(P>0.05); Treatment for 3 days,five days, 7 days three groups compared with before treatment were significantly different(P<0.05, P<0.01), SNK- q inspection found that sodium treatment 3 days Chinese medicine group and aescinate sodium group comparison difference has no statistical significance(P>0.05), the rest are differences comparing two different time points(P<0.05, P<0.01).The combination group analgesic effect is more obvious, especially in the treatment of 5, 7 days, was better than single treatment group, and with the increase of treatment time, the curative effect of Chinese traditional medicine group the pain also had seven Ye Zao glycosides sodium group obviously.6 Preoperative wait time: the comparison group difference was statistically significant(P<0.05), SNK- q test found that combination group compared with aescinate sodium group, Chinese traditional medicine group significant difference(P<0.01, P<0.05), Chinese medicine group compared with aescinate sodium group difference was statistically significant(P<0.05).The combination group can significantly shorten the preoperative swelling process, the most obvious curative effect, while Chinese medicine group took the second place.7 DVT positive aspects: three groups to compare difference has no statistical significance(P>0.05).8 Perioperative complications: combined treatment group, the Chinese medicine group compared with aescinate sodium group difference was statistically significant(P<0.05).Conclusion : After activating blood detumescence can effectively eliminate the ankle fracture early soft tissue swelling and pain, shorten the preoperative detumescence cycle, reduce the incidence of perioperative complications, is advantageous to the soft tissue repair as soon as possible,the clinical curative effect is distinct and safe.Huoxue Zhongtong Decoction is a clinical treatment of ankle fractures early soft tissue swelling and pain after effective prescription, economical and practical, safe and effective, has good clinical application value, worthy of clinical promotion. |
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