The Clinical Observation On The Treatment Of Steroid Resistant Nephrotic Syndrome With Dong Shen Pill

Objective: This subject aims to observe "Dong Shen Pills" hormone treatment resistant refractory nephrotic syndrome of qi and Yin deficiency syndrome clinical research, observation of traditional Chinese medicine treatment of hormone resistant nephrotic syndrome clinical efficacy and safety, to explore the optimal treatment of refractory nephrotic syndrome.Method: 60 cases in accordance with hormone resistant nephrotic syndrome of qi and Yin deficiency syndrome patients, randomly divided into treatment group and control group, 30 cases, control group support prednisone classic therapy and general treatment; Treatment group: on the basis of the control group treatment combined with "Dong Shen Pills". Two groups of a course of 8 weeks(if the pathological type of focal stage the glomerular sclerosis therapy 12 weeks), observe two groups of 24 hours urinary protein, blood lipid, renal function, plasma albumin, quantitative interleukins, interleukin-10,interleukin-4, liver function, blood routine, urine routine, electrocardiogram, and traditional Chinese medicine qi and Yin deficiency symptoms integral change, compare the curative effects.Results: The treatment group after treatment, patients with 24 hours urinary protein, renal function, plasma albumin, quantitative interleukin 10, interleukin 4 and clinical general curative effect, single symptom curative effect of traditional Chinese medicine, Chinese medicine clinical symptom integral and syndromes curative effect are obviously improved compared with before treatment, there was a significant difference compared with the control group. The blood routine, liver function, ECG without adverse effects.Conclusion: "Dong Shen Pills " joint prednisone hormone resistant nephrotic syndrome with obvious therapeutic effect, can significantly improve the patients’ clinical symptoms, reduce the side effects of prednisone, prevention and treatment of complications. On the clinical application of "winter kidney pills" is safe and effective, is a good method for the treatment of hormone resistant nephrotic syndrome is one of the correct use of "winter kidney pills" hormone treatment resistant nephrotic syndrome has a broad prospect.