| Objective: Through the retrospective study that had summarized clinical symptoms of colorectal cancer(CRC),the research aims to explore the regularity of syndrome distribution,and further analyze the correlation of colorectal cancer with the related factors,to strengthen the understanding of colorectal cancer,and provide clinical data to the treatment of colorectal cancer diagnosis and treatment,to guide clinical treatment.Methods: At first,designing a form about colorectal cancer clinical information,to collect the clinical information of 334 patients who meets the criteria,then,classify the syndrome type of traditional Chinese Medicine(TCM).The clinical information form has been finished and a database has been established.At last,using statistical methods to describe the distribution condition of CRC clinical data,summarizes the CRC distribution rule of TCM syndrome type,explore the correlation between TCM syndrome and CRC with personal general situation,clinical characteristics,tumor biological characteristics,treatment.Results: 1、Within this sample of 334 sufferers,patients’ average age was62.46 ± 12.740;84.4% among those older than 50;The rate of males and females was 1.32 :1;There were 79.6% from Guangxi;There were 58.7%ethnic Han,Zhuang Nationality and other ethnic minorities each were 29.6%、11.7%;Middle school culture level nearly 50%;Retired and jobless total more than 50%;More than 50% drinkers,smokers by 40%.2、The tumor located in rectum accounted for 45.2%;Differentiation in tubularadenocarcinoma accounted for 80.8%,moderately 62.6%;Stage Ⅲ and Ⅳtotal prevalence and stageⅠandⅡtotal prevalence was statistically difference(P < 0.05);Tumor metastasis is 60.2%,distant metastasis,liver metastasis was53.6%.3 、 From the point of view of treatment,patients who receive chemotherapy accounted for 34.1%,accounting for 50% of patients undergoing surgery.4、From the point of clinical characteristics,the shortest duration of 1 day,the longest duration for 17 years,the median duration of 6months.Hospital complained of abdominal pain and hemafecia,defecate habits change accounted for 60.8%,signs of abdominal scar,abdominal mass,abdominal tenderness are each more than 50%.There are 177 cases of patients with combined his disease,including gastrointestinal polyps accounted for43.0%.5、There were 6 types of syndromes of TCM.They are respectively damp — heat accumulate knot(26.6%),spleen kidney Yang deficiency syndrome(16.8%),stasis poison resistance(16.6%),weak spleen and stomach syndrome(14.7%),qi deficiency syndrome(14.1%),liver-kidney Yin deficiency syndrome(11.4%),after statistics analysis,damp — heat accumulate knot is the most common clinical evidence type(P < 0.05).The remaining five card type distribution there was no significant difference(P >0.05).6、Colorectal cancer syndrome has no obvious correlation with gender,age,marriage,culture degree,occupation,merging his disease,tumor site,pathological type,differentiation degree(P > 0.05),There are statistically significant with cases of stage,tumor metastasis,surgery,chemotherapy,admission departments,course(P < 0.05).Conclusion:1、Most of patients with CRC are elderly,men more than women;Mainly from Guangxi;The Han nationality were common,followed by Zhuang;Cultural degree is concentrated in the middle school;Professional was mainly content of retired;Smokers and drinkers are accounted for a significant share.2、The rectum is the most common cancer sites;tubularadenocarcinoma is the most common pathological type which developed moderately;to consider the pathological staging and tumor metastasis,the patient in our hospital have been in advanced.3、Surgery is still the most important treatment way of colorectal cancer.4 、 Abdominal pain,hematochezia,change in bowel habits,abdominal mass were mainly based on the analysis of colorectal cancer.Gastrointestinal polyps is the most common disease.5 、 The most common syndrome in our hospital is damp-heat accumulate knot,Yang deficiency of spleen and kidney is also accounted for a higher proportion.6 、 Colorectal cancer patients with gender,age,marital,culture degree,occupation,other diseases,tumor location,pathological type,differentiation degree will have no effect on colorectal cancer syndromes,case stage,tumor metastasis,surgery,chemotherapy,hospital departments,course of disease will influence type distribution of colorectal cancer syndrome. |
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