The Clinical Investigation Of Chaihu Shugan Mingmu Pill In Treatment Of Chronic Anterior Uveitis Of Liver Depression And Kidney Deficiency With Blood Stasis

Objective:To observe and evaluate clinical effect of Chaihu Shugan Mingmu pill in the treatment of Chronic anterior uveitis of liver depression and kidney deficiency with blood stasis.Methods:60 patients(86 eyes)of Chronic anterior uveitis of liver depression and kidney deficiency with blood stasis,in accordance with the random number table,were divided into treatment group and control group;30 cases(44 eyes)in treatment group taken Chaihu Shugan Mingmu pill,30 cases(42 eyes)in control group taken Prednisone Acetate Tablets orally in need,meanwhile offered Vitamin D Chewable Tablets,Potassium Citrate Granules and Omeprazole Enteric-coated Tablets as adjuvant therapy.The patients of two groups were all given local treatment such as Atropine Sulfate Eye Gel and Tobramycin-dexamethasone eye drops.The two groups were cured the three courses and Each course of 30 days.After 90 days of treatment,the changes of two groups of patients with vision,ocular abnormal signs score,the symptomatic score of TCM were observed,then evaluating clinical curative effect.And all patients were followed-up for 6 months after the treatment,observe the recurrent rate.Results:(1)Two groups of patients with clinical efficacy comparison: the treatment group44 cases,10cases of clinical cure,18 cases of success,12 cases of effective,4cases of non-effective,the total effective rate was90.9%;the control group42 cases,3cases of clinical cure,12 cases of success,19 cases of effective,8cases of non-effective,the total effective rate was80.95%,Through statistical software analysis found that there were significant difference(P<0.05),therefore,the treatment group curative effect was better than the control group;(2)Compared with the two groups of eyesight,there were no significant difference before treatment(P>0.05),it were compable.Compared with before and after treatment,the two groups were obviously differences(P<0.05),so both of two treatments trategies could improve patients' vision,and the treatment group improved significantly.(3)Compared the two groups of eye symptoms integral:there were no significant difference before treatment(P>0.05),it were compable.Compared with before and after treatment,the two groups were obviously differences(P<0.05),so both of two treatments trategies could improve physical sign of eye,and the treatment group improved significantly.(4)Compared the two groups of TCM symptoms curative effect:the total effective rate of the treatment group(86.67%)was superior to the control group(66.67%),which had significant difference by statistical analysis(P<0.05),it showed that the curative effect of treatment group is better than the control group.(5)Compared the recurrence rate:After treatment,all patients were followed up for 6 months,the treatment group had 6 cases(8eyes)of recurrence,the recurrence rate was18.18%,intsead the control group had 26 cases(33eyes)of recurrence,the recurrence rate was78.57%.By statistical analysis,P<0.05,there were significant differences,it suggestted that Chaihu Shugan Mingmu pill can reduce the recurrence rate.Conclusion:Chaihu Shugan Mingmu pill had definite clinical effect in treatment of the Chronic anterior uveitis of liver depression and kidney deficiency with blood stasis.It can improve the patients' vision,relieve symptom of eye ministry unwell,improve the patients' systemic symptoms,and significantly prevent the recurrence rate.