A Systematic Analysis On The Risk Factors Of Disease Progression Of 112 Patients Suffered From Recurrent Chest Pain After PCI

Objective:To investigate the incidence of disease progression after PCI and the relevant risk factors, providing some reference for clinical management. Methods:112 patients suffered from recurrent chest pain after PCI were admitted in WuhanTongji hospital from Feb.2015 to Feb.2016 for coronary artery angiography(CAG). According to the CAG, the patients were divided into three groups:no restenosis group(71cases),in-stent restenosis group(30cases) and out-stent stenosis group(11cases). Information such as risk factors(age, sex category, body mass index, hypertension, lipid profile, blood sugar levels and smoking history), follow-up intervals and previous PCI records(Coronary artery lesion extent, the number of stents, stent size) were collected and analyzed in different groups respectively. Results:The incidence of restenosis after PCI in patients suffered from recurrent chest pain is 26.8%. Compared to the no restenosis group, the out-stent stenosis group had a lower body mass index;compared to the no restenosis group,the in-stent restenosis group had a higher blood cholesterol level and more diffused coronary artery lesion. History of diabetes and multiple stents are risk factors of in-stent restenosis. As to other risk factors,such as age,gender,history of high blood pressure, lipid profile(TG,HDL,LDL),glycated hemoglobin levels, smoking history, follow-up intervals and stent size, there is no significant difference among the three groups. Conclusion: CAG is necessary for patients suffered from recurrent chest pain after PCI. Coronary lesion progression(including out-stent stenosis and in-stent restenosis) were detected in about one-third cases(36.6%).Patients with higher blood cholesterol levels and more diffused coronary artery lesion are more likely to suffer from in-stent restenosis after PCI. History of diabetes and multiple stents are risk factors of in-stent restenosis.